Gates etiketine sahip kayıtlar gösteriliyor. Tüm kayıtları göster
Gates etiketine sahip kayıtlar gösteriliyor. Tüm kayıtları göster

18 Şubat 2017 Cumartesi

Bio-terrorism could kill 30 million people in a year, says Bill Gates – video

Bill Gates, the co-founder of Microsoft who has spent billions on philanthropic efforts over the past several decades, speaks at the Munich security conference on Sunday and says that the world must be on guard for bio-terrorism attacks. Telling the audience that “a synthetic version of the smallpox virus … or a super contagious and deadly strain of the flu” could kill more than 30 million people in a year, Gates says there is a “reasonable probability” that such an event could occur in the next 10 to 15 years



Bio-terrorism could kill 30 million people in a year, says Bill Gates – video

14 Şubat 2017 Salı

Trump"s "global gag" aid rule endangers millions of women and children, Bill Gates warns

The “global gag rule” imposed by Donald Trump, blocking US funds to any organisation involved in abortion advice and care overseas, could impact millions of women and girls, endangering their lives and those of their babies, Bill and Melinda Gates have warned.


The changes are expected to result in funding from the world’s biggest donor to family planning and women’s health programmes in the developing world being slashed. It could, Bill Gates told the Guardian, “create a void that even a foundation like ours can’t fill”.


Gates and his wife spoke out as they published a progress letter to Warren Buffett, the businessman who 10 years ago invested a large part of his fortune in the couple’s foundation which has at its centre the mission to save children’s lives. Empowering women and girls, the couple said, was central to that aim.


Trump signed an executive order reimposing the Mexico City policy, also known as the global gag rule, on his first full day in office. Republican presidents since Ronald Reagan in 1984 have imposed the policy, while their Democrat counterparts have lifted it. The rule strips funds from any organisation that “performs or actively promotes abortion as a method of family planning” overseas.


But Trump’s order goes further, applied to any organisation that receives funding from US Aid , not just those involved in family planning. That expansion, said Melinda Gates, was a surprise.


“We’re concerned that this shift could impact millions of women and girls around the world,” she said. “It’s likely to have a negative effect on a broad range of health programs that provide lifesaving treatment and prevention options to those most in need.


“This includes programmes that prevent and treat HIV, TB and malaria, and provide healthcare to women and children around the world. Enabling women to time and space their pregnancies and providing access to treatment and prevention of infectious diseases is lifesaving work. It saves moms’ lives and it saves babies’ lives, and that has long had wide support in the United States.”


Bill Gates said their foundation would not be able to bridge the potential funding gap. “The US is the No 1 donor in the work that we do. Government aid can’t be replaced by philanthropy. When government leaves an area like that, it can’t be offset, there isn’t a real alternative. This expansion of this policy, depending on how it’s implemented, could create a void that even a foundation like ours can’t fill.”


He had an early phone call with Trump in November and then a meeting in December with the president-elect in New York, he told the Guardian. They talked about the eradication of polio, which Gates hopes could come as early as this year, and the research his foundation is supporting towards an Aids vaccine and ways to protect people from pandemics such as Ebola in west Africa.


“So that was a good discussion – the fact that he was interested in having me talk about the Foundation’s work – I was pleased,” said Gates.
But the philanthropist did not anticipate the scope of the executive order affecting family planning, an issue at the centre of the foundation’s work, that Trump was to sign.



Bill (L) and his Melinda Gates (C) with Warren Buffett as the latter pledge of 10m shares of Berkshire Hathaway to the couple’s foundation.


Bill and his Melinda Gates with investment veteran Warren Buffett (R) in 2006. Photograph: Nicholas Roberts/AFP/Getty Images

The letter to Buffett is an assessment of the progress the Gates Foundation has made since 2006, when he pledged 10m shares in his company Berkshire Hathaway in annual instalments worth a total of $ 31bn at the time. The couple write of the progress that has been made in saving children’s lives, particularly through immunisation and vaccine development, and the work that lies ahead in making childbirth safer and tackling malnutrition.


Their letter makes clear what is at stake with Trump’s move to reimpose the global gag rule, arguing that women and maternal health are key to so many global health issues.


Empowering women is a key theme of the letter in which the couple argue that enabling women to access contraceptives control over the number of pregnancies they have is crucial. When women have a gap of at least three years between births, their children are more likely to survive and be healthy and well educated, the couple say. “Like vaccines, contraceptives are one of the greatest lifesaving innovations in history,” writes Bill Gates in the letter.


What is the ‘global gag rule’, and why does Trump support it?

Since they set up their foundation its focus has shift from the hunt for technological solutions towards social change. The attention to women’s empowerment came from the evidence, the couple say.


“You cannot go out and be in the developing world and then come back and look at the data and turn away from the importance of women in the developing world,” said Melinda Gates.


Whether they breastfeed and take their children to be vaccinated makes a profound difference to how the child grows and his or her life chances, and men are not always there, she added. “So you have to look at the woman’s role and when you look at it you realise it can be an accelerator to every single thing you want to have happen in the world for global health and global development and social change.”


In their letter, Bill Gates sats that poverty is sexist, a phrase he first heard from the U2 frontman Bono.


“The poorer the society, the less power women have. Men decide if a woman is allowed to go outside, talk to other women, earn income. Men decide if it’s acceptable to strike a woman. The male dominance in the poorest societies is mind-blowing.”


In the letter, Melinda Gates adds: “It’s also crippling. Limiting women’s power keeps everyone poor.”


She and her husband tell of their visits to sex workers in India whom the couple say they encouraged to form self-help groups, thinking the women would help each other insisting their clients wore condoms to protect themselves from HIV. That vision, said Bill Gates, “was way too narrow”. The sex workers began to support each other in every aspect of their lives.


“Warren, if Melinda and I could take you anywhere in the world so you could see your investment at work, we probably would take you to meet sex workers. I met with a group in Bangalore, and when they talked about their lives, they had me in tears,” writes Bill Gates.


“One woman told us she turned to sex work after her husband left her – it was the only way to feed her children. When people in the community found out, they forced her daughter out of school, which made the girl turn against her mother and threaten to commit suicide.


“That mother faced the scorn of society, the resentment of her daughter, the risks of sex work, and the humiliation of going to the hospital for an HIV test and finding that no one would look at her, touch her, or talk to her. Yet there she was, telling me her story with dignity.”



Bill and Melinda Gates receive medals from Obama at presidential medal of freedom ceremony in November 2016.


Bill and Melinda Gates receive medals from Obama at presidential medal of freedom ceremony in November 2016. Photograph: Carlos Barria/Reuters

There have been setbacks, such as the failure yet to end polio, but the couple emphasise the enormous progress that has been made in the last couple of decades in global health and speak in the letter of their optimism for the future.


“Polio will soon be history. In our lifetimes, malaria will end. No one will die from AIDS. Few people will get TB. Children everywhere will be well nourished. And the death of a child in the developing world will be just as rare as the death of a child in the rich world.


“We can’t put a date on these events, and we don’t know the sequence, but we’re confident of one thing: The future will surprise the pessimists.”



Trump"s "global gag" aid rule endangers millions of women and children, Bill Gates warns

30 Aralık 2016 Cuma

Bill Gates: world faces decade at risk from antibiotic-resistant bugs

People across the world, particularly those in developing countries, face a decade at risk from pandemics spread by antibiotic-resistant bugs, the billionaire Bill Gates has warned.


Gates, who made his fortune with the Microsoft Windows operating system before becoming a philanthropist, said the success of antibiotics had created complacency that was now being exposed by the rise of microbial resistance to the drugs.


“I cross my fingers all the time that some epidemic like a big flu doesn’t come along in the next 10 years,” Gates told a special edition of Radio 4’s Today programme guest-edited by Dame Sally Davies, the chief medical officer for England.


“I do think we will have much better medical tools, much better response, but we are a bit vulnerable right now if something spread very quickly like a flu that was quite fatal – that would be a tragedy and new approaches should allow us to reduce that risk a lot.”


Gates said it was crucial for wealthier countries to step in to help the developing world fight disease, both for humanitarian reasons and for their own health security.


Although mistakes were made, criticism of the World Health Organisation (WHO) during the Ebola crisis in west Africa was unfair, he said, because it was not funded or staffed to do all the things that observers wanted it to do.


International cooperation had led to the eradication of smallpox, and was on the verge of eradicating polio, he added.


“The cooperation that we have seen, I think, needs to intensify,” Gates said. “It’s the only way that global problems like epidemics will get solved and so [for] all the people who are negative on WHO, the message to take away from that is not that that kind of multilateral cooperative effort is doomed and the money is not well spent, rather that we actually need to broaden their capacity. We actually need to dedicate ourselves to this global cooperation.”


In September the UN secretary general, Ban Ki-moon, warned that antimicrobial resistance was a “fundamental threat” to global health that risked making high quality universal healthcare impossible.


It is estimated that more than 700,000 people die each year from drug-resistant infections, though it could be much higher because there is no global system to monitor the figures. There has also been difficulties in tracking death tolls even in places where they are monitored, such as the US, where tens of thousands of deaths have not been attributed to superbugs, according to a Reuters investigation.


The European Centre for Disease Prevention and Control reported in November that illnesses resistant to so-called last-line antibiotics – drugs kept in reserve for use against pathogens that have proved resistant to all other antibiotics – were on the rise in the continent.


Without them, some infectious diseases could become untreatable and some forms of major surgery would again become perilous.


Davies said Britain’s health service was well placed to handle a flu pandemic, although it would still take as long as six months to “produce enough vaccine to start putting it into people”. She was less optimistic about how resilient the rest of British society would be to an outbreak.


“It’s not just the NHS,” she said. “It’s how would our social care system cope with people who aren’t ill enough to be in hospital but need extra support? It’s how would our economy cope if a large proportion are too ill to work? When we have a just-in-time ordering policy for delivery of food, petrol, whatever.


“And if you think about the issues that could happen here if we had a recurrence of the 1918 type flu, then what would it be like in middle- and low-income countries where they don’t have the health systems to look after the patients?”



Bill Gates: world faces decade at risk from antibiotic-resistant bugs

8 Temmuz 2014 Salı

"Remote-control" contraceptive implant produced backed by Bill Gates

Currently the contraceptive implant the NHS offers lasts three many years but if a lady wishes to get rid of it just before then, she should attend a clinic.


The creators think it will be much more convenient and if it passes safety exams, it could be on the market place as early as 2018. They stated it would be “competitively priced”.


Pre-clinical testing of the implant, designed by start-up MicroCHIPS in Massachusetts, will start up coming 12 months.


The idea for the chip originated two years in the past. Throughout a go to to Massachusetts Institute of Technology’s (MIT) lab, Gates and his colleagues asked Robert Langer, professor at MIT, regardless of whether it was achievable to generate birth manage that a girl could turn off and on.


MIT explained the implant would have to be encrypted to protect wireless data movement and maintain it safe.


The chip’s dimension is 20mm x 20mm x 7mm and reservoirs of the hormone are stored on a 1.5cm-wide microchip inside of the device.


The implant’s everyday dose performs by a little electric charge melting an ultra-thin seal close to the hormone. This would then release a 30 microgram dose into the entire body.


The co-creator of the chip, Dr Robert Farra, mentioned that the manage would have to be close sufficient for skin contact.


“Someone across the room are not able to reprogram your implant,” Dr Farra, from MIT, explained.


He additional: “The capability to turn the device on and off gives a particular convenience factor for people who are organizing their household.”


However the chip would not be without having its difficulties in accordance to Simon Karger.


The head of surgical and interventional company at Cambridge Consultants informed the BBC implanted technology faced some apparent hazards and difficulties.


Mr Karger explained he could “foresee a potential in which a massive selection of problems are treated via wise implanted systems”.



"Remote-control" contraceptive implant produced backed by Bill Gates

26 Mayıs 2014 Pazartesi

Melinda Gates on the worldwide family planning revolution video

Two many years on from the London Summit on Family members Planning, Melinda Gates, businesswoman and co-chair of the philanthropic Bill and Melinda Gates Foundation, discusses the progress produced on tackling the issue. She explains how initiatives to widen entry to contraception have had a good impact on girls and ladies in creating nations. She also stresses the relevance of sexual wellness training in nations such as Niger, which has one of the highest fertility prices in the world



Melinda Gates on the worldwide family planning revolution video

24 Mayıs 2014 Cumartesi

Melinda Gates: I wrestled with my faith - but females need contraception


As a Catholic Melinda Gates admits she has wrestled with her faith above the concern of contraception, but says eventually she could not ignore the “rallying cry” of ladies from all in excess of the globe who require the resources to strategy their very own families.




“I would be out talking to ladies about vaccines – what I was interested in … and the females would say, ‘yes that’s crucial but what about that contraceptive instrument.’”




“So it grew to become a rallying cry for me to reply individuals women’s call, so yes, I wrestled with my faith and I’m Catholic and I use contraceptives and I believe in them and I think it truly is the right point for girls all more than the world.”




As joint head of the Gates Foundation with her husband, Bill, Melinda presides over an organisation whose endowment of $ 39 billion (much more than £23 billion), dwarfs the economic system of many nations.




When she addressed the Globe Health Assembly in Geneva this week, she urged international action on the largely preventable fate of people 5.5 million newborn babies who die every single 12 months without having leaving any trace that they ever lived. However her wider focuses are the irreducibles of daily life and death, her methods – vaccines, mosquito nets and contraception.




Melinda Gates: I wrestled with my faith - but females need contraception

Melinda Gates: "You have to let your heart break"

When she addressed the Globe Overall health Assembly in Geneva this week, she urged international action on the largely preventable fate of these 5.5 million newborn infants who die every single 12 months with out leaving any trace that they ever lived. Even though her wider focuses are the irreducibles of lifestyle and death, her techniques – vaccines, mosquito nets and contraception – are the armoury of a steely businesswomen.


We meet for the duration of her flying visit to see the growth secretary, Justine Greening, and to collect the honorary award of Dame of the British Empire, bestowed on her earlier this 12 months in recognition of her work for philanthropy and worldwide development. As ever, she is total of praise for Britain and its givers. “I’d enjoy to see your Red Nose day go on around the globe. You are a really generous country,” she says, also pointing to the six million children’s lives saved by the International Alliance for Vaccines and Immunisations (GAVI) to which the Uk is one particular of the biggest donors.


Where some could settle for pious hopes, Melinda Gates would like information. Unlike her husband, she does not declare herself proud to be a geek, but nor does she disassociate herself from that label. “A good deal of my buddies would say that I’m kind of a datahead also.”


On the calculus of human lifestyle, newborn babies – her emphasis this week – fare specifically badly. Analysis just published in the health-related journal The Lancet displays that the toll of 15,000 babies who are born and die each and every day without having even receiving a piece of paper, let alone any memorial, is largely preventable. Provided the attrition, why has the target come so late?


“The fantastic news in child mortality is that the amount has come down substantially. Twenty million utilized to die each single yr, which is a tragedy. We’ve got that amount of children under 5 down to 6.six million dying a yr – still far too numerous but an unbelievable charge of progress.” On newborns, enhancements have been much slower. Deaths of newly-born babies now account for 44% of all beneath 5 kid deaths.


Mrs Gates can make the situation for inexpensive and straightforward indicates to keep away from so numerous deaths. “Teaching a female to preserve her child warm and instant breast feeding are not quite pricey. But if we as a planet focus on [measures like] that, we will cut in half however again people 6.six million children who are dying.”


Charities this kind of as Save the Kids have emphasised a lot more expensive interventions, too – in particular, a lot of more midwives. “In Ethiopia and Rwanda they have got local community health workers, who are primarily midwives, out in the neighborhood. That qualified assistant can save a women’s lifestyle and – by carrying out some fundamental factors – conserve the newborn’s lifestyle. Other countries in Africa are commencing to replicate that model.”


There was little in Melinda Gates’s personal early existence to recommend what her vocation would be. Born in Dallas in 1964, a couple of months right after John F Kennedy was shot, Melinda Ann French was the daughter of an engineer who set up a rental enterprise to put his 4 children through school. “We worked on the properties. I mowed lawns, I scrubbed ovens, and I cleaned homes right after individuals left.”


She also kept the company books on a rudimentary property Pc before moving on to a pc science degree and then joining Microsoft, in which she met the company founder, Bill Gates, by likelihood at a conference dinner. “There have been only two chairs left. I took one and, and 20 minutes later on, an individual else who was even later on took the final one particular next to me. That was Bill.”


To celebrate their engagement, they organised a lavish African safari for a group of friends. Unbeguiled by the luxury and wildlife, the Gateses came property preoccupied instead by the memory of girls weighed down by firewood and young children. Shortly after their marriage, she left her higher-flying occupation to increase her 3 young children and set up the basis that has grow to be a template for other billionaire philanthropists. Along with Warren Buffett, the Gateses have so far inspired, or persuaded, much more than 120 fellow wealthy-listers to pledge at least half their fortunes to charity.


Bill and Melinda Gates in India’s Bihar’s state on March 23, 2011 (HO/AFP/Getty Photographs)


In which a lot of titans of business leave their cash to their heirs, the Gateses plan rather to bequeath their sense of duty, along with only a small fraction of a fortune destined largely for charitable ends. “We speak about the problems we see in the developing planet at the dinner table with the little ones. They’re quite properly-informed. Possibly we speak a little bit also significantly about tuberculosis or HIV/Aids. Other households may be a little bored, but we’re passing our values on to our youngsters.”


As properly as visiting developing countries in school holidays, the Gates kids – two teenage daughters and a son – “all have chores around the home. You bet. And they also each and every work in a local charity in Seattle. They’ve picked ones shut to their heart, and they do hands-on work there anonymously. They’re learning to volunteer and give back.


“We have an agreement inside of the family members about how a lot income they will each get, and we believe our kids should go off and have their own careers and their personal lives.” Although the foundation will be wound up following the death of the last surviving partner, she anticipates no allow-up in their work for decades to come. “These are our most energetic many years, so we want to get on. We’ll nonetheless be concerned in vaccine perform in ten many years, and we’re hunting twenty many years ahead at maternal and kid mortality.”


For all the progress she can cite, sections of the West remain sceptical about the use of assist. The potency of this argument might be illustrated by the fact that she and Bill chose to use their most recent yearly newsletter to try and debunk some myths surrounding help for example, suspicion that conserving more children’s lives will boost the global population to unsustainable levels.


From the time of Thomas Malthus, who published his famous essay on the topic in 1798, theorists have worried about a doomsday situation in which food supply can no longer sustain an in excess of-crowded planet.


As Melinda writes in the newsletter: “Letting children die now so that they don’t starve later does not work. It may possibly be counter-intuitive, but the countries with the most deaths have amid the quickest-growing populations in the globe.” When there is no ensure that a youngster will live, and every possibility that it will die, mothers tend to have a lot more and more children.


In Afghanistan, exactly where little one mortality is very substantial, ladies have an average of 6.2 children. Despite the fact that one particular in ten kids will die, the country’s population is projected to develop from 30 million these days to 55 million by 2050. In Thailand, by contrast, ladies went from possessing six young children to two in excess of the course of two decades as the consequence of a government-sponsored household planning programme. Nowadays, little one mortality in Thailand is roughly the same as the US – and the regular Thai mom has one.6 babies.


As a devout Catholic, Melinda Gates struggled before selling contraception. “Absolutely. But women’s stories would ring in my head. They would say: ‘I cannot have an additional child. I previously have 4, and I can barely feed them.’ It grew to become a rallying cry to me to response those women’s phone. So yes, I wrestled with my faith but I’m a Catholic, and I use contraceptives, and I consider it’s the proper thing for women all more than the world.”


Will the Pope, to whom she has thrown down a gauntlet, adopt her message? “I feel the Pope will consider the selections he thinks are proper for the church. I do not believe he’ll automatically adhere to my messages, but I believe he cares about the poor. If he’s out speaking with households, he will hear – I hope – the genuine needs on the ground.”


When I ask once more if Pope Francis is persuadable, she says: “Religious institutions come all around to things more than time. This is a moral determination that the Catholic church feels it demands to make, so I am hopeful, but we will see.” Of abortion – nonetheless hugely controversial in the US – she says: “People have distinct opinions about abortion for a very excellent cause. The debate even now requirements to occur in my country. If we can get girls contraceptives, you will not get them into the predicament where they require to have an abortion. I’ve never met a lady in the planet who wished an abortion.


“African nations have to determine for themselves. Most nations we operate in do not let abortions.” The US, meanwhile, stays professional-option. “Would I repeal that law? No, I would not. The country has determined that females must be allowed to have [that option], so I surely wouldn’t turn it back.”


The operate they have undertaken, along with charity and government partners, has altered the globe. The Gateses’ funds, coupled with rigorous business practice, enables Bill to say that there will soon be no poor nations left, or Melinda to speak of a drop from 20 to six.6 million in the below-fives who die every 12 months.


But, while no one particular doubts the value of their achievements, some question no matter whether the rich must have such sway more than life and death. She counters that charge by citing “checks and balances [which] actually have to do with being transparent. Our basis is transparent. All our grants are on internet site, and there is transparency in [our] data. We feel very accountable.”


Other observers think that the wealthiest, whose fortunes are on the rise, could afford to contribute a fantastic deal more. Exactly where the Gateses do have British signatories to their giving pledge – Sir Richard Branson and Lord Ashcroft amid them – the culture of philanthropy is far far more embedded in the minimal-tax US than In Britain. When Bill Gates tries to drum up support from the super-rich in booming economies, this kind of as China, he stresses that alleviating poverty and unwell wellness pays financial dividends saying that, “the returns from investing in bad people are just as excellent as from investing in the enterprise planet – and have even much more which means.”


As Melinda suggests, there is nothing arbitrary about the Gates operation. Her watchwords – transparency, accountability and information – are the mantras of the boardroom, and the Gates model of entrepreneurial danger-taking, innovation and partnership is intended to match the company template of great practice. There is practically nothing, in other words, to frighten off an ardent capitalist in a system the place every single vaccine administered, mosquito net dispensed and life saved is logged and monitored.


Bill and Melinda Gates during their 2011 trip to Bihar state, India. (AP Photo/Aftab Alam Siddiqui)


In a new departure, African girls are doing door-to-do surveys with cell phones and downloading the findings to a information bank that offers true-time info to the Gates Basis. Melinda Gates might be a amount-cruncher, but her most respected database is the lives of other women. “It’s very emotional. You meet ladies who ask you to get one particular of their children home with you. You know that little one would be better off, but you can’t.


“Before coming property, I always consider time to reflect. What did I get on emotionally? What may possibly inform our techniques?” As she re-enters lifestyle in the Gates mansion, ferried by private jet, she might also reflect on how the bleak existences she witnesses contrast with her own seemingly charmed daily life.


Her marriage, for instance, would seem a model of perfection, in which she and Bill are so ideally suited that they even have matching his ‘n’ hers honorary degrees from Cambridge University, a recipient of the Gates largesse. She is eager to dismiss any notions of undented harmony.


“There’s no such factor as excellent, and I really don’t consider we must perpetuate that myth. There’s a good deal of [speak ]in the US about ladies being ideal as properly as this myth of the best couple. It is not reasonable, and girls and women shouldn’t expand up below that pressure. I have close friends and siblings who are in amazing marriages, but they are nothing at all like mine.


“I don’t consider there’s any perfect marriage, but we do have a especially sturdy one particular. We’re fortunate to have located a passion and to share what we understand and where our hearts are.” So do they fall out? “Oh, certain. Each and every couple has issues that irritate the other a single.” This kind of as? “I’ll inform you what Bill’s irritant is about me. He does not like the way that I chew ice cubes.”


For the initial years they were collectively, she clung to her anonymity far a lot more jealously than to her income. “Then I decided that, if I could give voice to some of the females who talked to me, it was worth giving up some privacy, even though I am a very personal man or woman. But there are nonetheless areas in Seattle where I can walk into a sandwich shop and most men and women have no thought who I am. I have a pony tail and my yoga pants on and a stack of papers to study.”


People paperwork detail other people’s tragedy. Numerous occasions, she has been diminished to tears by an encounter with yet another distraught mom carrying an additional dying child. She might possess the aura, retinue and safety detail befitting a monarch or a president, but this kind of trappings provide no safety against human grief.


“You have to let your heart break,” she says. “That is what enables me to get action.” In the disciplined crusade of Melinda Gates, not a penny of her fortune nor a single stranger’s cry of ache ever knowingly goes to waste.



Melinda Gates: "You have to let your heart break"

28 Nisan 2014 Pazartesi

Melinda Gates on the 9 players shifting the vaccine game

Melinda Gates

Melinda Gates is co-founder of the Bill and Melinda Gates Basis. Photograph: Stuart Isett/Polaris




His Highness Common Sheikh Mohammed bin Zayed bin Sultan Al Nahyan, Crown Prince of Abu Dhabi


The Crown Prince is a foremost champion in the Middle East for enhancing youngster well being. He is creating positive kids in Afghanistan and Pakistan receive the polio vaccine, and he’s investing in strengthening immunisation systems in each countries. In April 2013, he co-hosted the Worldwide Vaccine Summit in Abu Dhabi, where $ 4bn was raised to finish the task on polio eradication and defend kids everywhere from preventable ailments.


Dr Agnes Binagwaho, Rwandan minister of health


Thanks in portion to minister Binagwaho’s leadership, Rwanda’s vaccination coverage rates for several conditions exceed those in the US. Since 2000, youngster mortality is down by two-thirds. In 2012, Dr Binagwaho greeted a rotavirus vaccine shipment at Kigali’s airport, celebrating that Rwanda was the very first nation in east and southern Africa to introduce the vaccine. Binagwaho proves that sturdy leaders can make certain their individuals get outstanding healthcare.


Salim Sheikh and Sikha Patra


These two youthful teenagers starred in the 2013 documentary, Revolutionary optimists, which displays how some of the poorest communities in India mobilised to vaccinate each and every single child against polio. Final yr, I interviewed Salim and Sikha, and I was blown away by how much they’d already achieved – and by how ambitious they were about the a lot of issues youth advocates could do to make their communities better.


Dr Margaret Chan, director-general of the Planet Overall health Organisation


Dr Chan place immunisation on top of the global health agenda. She drove the international vaccine action strategy, a roadmap for receiving all young children the vaccines they want by 2020. The strategy includes commitments to finish polio, strengthen routine immunisation and enhance pharmaceutical organization contributions to the international vaccine supply, which will aid make vaccines cheaper. The WHO not too long ago approved a Chinese-produced vaccine for Japanese encephalitis for the very first time.


Aliko Dangote, founder, president and chief executive officer of the Dangote Group and chairman of the Dangote Foundation


Africa’s richest man is using his fortune and his organization networks to improve public health in the continent’s most populous nation. He is working with our foundation and the Nigerian government to improve immunisation coverage and attain polio eradication in his home country, one particular of just 3 exactly where the condition is even now endemic.


Centre for Understanding Societies


India’s top innovation consulting firm is creating confident that immunisation techniques perform for the people who use them. CSK performed the investigation that led to data for daily life, a contest to redesign a country’s childhood immunisation card. Its Bihar Innovation Lab is now beginning to check new patterns in Bihar state, informed by the two the information for daily life process and their prior operate. Like the basic checklists that have enhanced emergency care in several hospitals, new immunisation cards that are resilient and include added essential info are a standard innovation that will advantage millions of kids.


Margarida Matsinhe, discipline officer, Village Reach and Gates Basis vaccine innovation award winner, 2013


Margarida Matsinhe, aided overhaul Mozambique’s immunisation program by focusing on the seemingly mundane difficulty of logistics. Her tireless emphasis on the basics vastly enhanced the method for maintaining vaccines cold from forty% of the time to 96% of the time. The regular monthly incidence of rural wellness centres not obtaining life-conserving vaccines in stock dropped from a staggering 80% to 1%.


Gavi Alliance


The Gavi Alliance is fighting inequity by helping make sure new and underused vaccines are available to – and cost-effective for – the countries that want them most. Since its creation Gavi has reached 440 million kids in 73 countries with life-conserving vaccines they need. Later this year, the pentavalent vaccine – a single vaccine that protects against five main childhood conditions (hepatitis B, Haemophilus influenzae kind b, diphtheria-tetanus-pertussis) will be launched in the final Gavi nation that does not use it. In these countries, the place it can be challenging to reach children, combining numerous vaccines into one is a easy innovation that saves lives. By 2020, the Gavi Alliance estimates that pentavalent vaccines will avert much more than seven million deaths.


Melinda Gates is a businesswoman and philanthropist, and co-founder of the Bill and Melinda Gates Basis. Follow @melindagates on Twitter


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Melinda Gates on the 9 players shifting the vaccine game

3 Nisan 2014 Perşembe

Bill Gates: world need to stage up battle towards neglected tropical illnesses

Bill Gates believes the globe can and need to step up the fight towards a group of tiny-known and prolonged-neglected tropical diseases, that collectively do as significantly harm as HIV, malaria or tuberculosis.


In an unique interview with the Guardian, the founder and former boss of Microsoft explained the funds has to be discovered, even in the existing difficult economic climate, for very efficient programmes, such as the mass delivery of drugs that can avert diseases such as schistosomiasis and trachoma.


“I think we’ll be capable to increase the funds. It’s variety of like vaccines – you’d really feel awful if you didn’t increase the cash,” he stated. But, “it may take us a couple of many years to get up to where we are carrying out all these mass drug administration programmes at the intensity we’d like to.”


Everyone recognises the damage done by HIV, but few realise the burden of sickness and disability induced by the group of illnesses recognized by the billionaire philanthropist, which are transmitted mainly by parasites, flies and worms. One particular in 6 men and women globally is at threat. And by contrast with the huge 3, significant strides in direction of controlling some of the illnesses are taking location.


“If this was a single illness and the entire burden was attributed to one particular disease, it would be correct up there with the big conditions,” stated Gates. “As a group … the human burden [in terms of disability] is pretty gigantic. I place this entire programme up there with what’s going on with malaria, what’s going on with TB, what’s going on with HIV – it is some thing that folks ought to be quite fired up about the progress which is been made.”


Gates was speaking from Paris, where he was taking portion in a meeting to search at the progress manufactured against ten neglected tropical ailments in the final two years. In January 2012, Gates convened an unprecedented meeting of the CEOs of 13 key drug businesses – usually rivals – as effectively as international wellness organisations and governments in London, who all signed a declaration, pledging to do what they can to control or remove them.


Gates mentioned he was “super-content” with the progress so far. The pharmaceutical organizations have increased their donations of existing medicines that can avoid some of the illnesses and are helping to investigate potential new medicines for diseases exactly where there are inadequate therapies.


“We’re super-pleased with what they’ve carried out on two fronts – the drug donation front, where they’re ramping up the capability and helping with the logistics, to get this things delivered, and the second is on the diagnostic and drug front to search at in which we even now have gaps.


“The best information story we have here is that we have a new diagnostic for sleeping sickness and we have a drug that, though it is in a phase two [trial], seems to be quite promising as an oral treatment for this.”


Sleeping sickness, or African trypanosomiasis, spread by the bite of the tsetse fly, is fatal with no remedy. A quarter of these contaminated are kids. Diagnosis at the moment requires a lumbar puncture, and if the patient is lucky enough to get a single, they will require intravenous medication for days. In some locations, there is nothing at all greater than an arsenic-derivative, which kills 5% of these taken care of. But with the new diagnostic test and probably a pill, the prospects are transformed. Authorities are now for the very first time talking about getting rid of the disease by 2020, rather than just controlling it.


There is a clear elimination purpose for just one of the illnesses – guinea worm, which the Carter Foundation has targeted on for numerous many years. “We’re down I feel to 148 circumstances final year and it truly is in Mali and there were a few cases in Chad and south Sudan. So we’re very close on that. It truly is turned out with the unrest in Mali and South Sudan they are not going to make the unique date for it and so we’re possessing to put much more into that,” stated Gates.


But real eradication is difficult and not usually appropriate. “For most illnesses you never want to try out and do eradications, due to the fact eradications are really difficult and you end up investing a whole lot on the last tiny variety of circumstances and only if you genuinely think you can do well and you are stopping it from coming back, then it gets very worthwhile, as it is in the situation of polio,” explained Gates, who has put substantial money and hard work into the attempt to rid the planet of polio. “So we’re quite mindful about when we get individuals riled up to think correct, true eradication.”


Greater drugs could modify the outlook for young children contaminated by roundworm, hookworm and whipworm – the 3 most widespread of the soil transmitted helminths – and also for onchocerciasis. Current medication only destroy the juvenile type of the worm.


“It signifies you have to maintain coming back and catching the hatched worms again and yet again and once again for a great deal of many years. If you can destroy the grownup worm, which is the human reservoir and it would assist a whole lot,” explained Gates.


There are now R&ampD agreements with drug firms to investigate. In the meantime, country programmes have in the last couple of many years been created to dose kids and adults with medicines not for a single ailment, but for all people lively in their area. That expenses thirty cents a particular person, said Gates – not thirty cents per man or woman, per disease.


A lot more funds was announced in Paris, like $ 50m (£30m) more from the Bill and Melinda Gates Foundation, $ 50m from the Children’s Investment Fund Foundation and $ 120m from the Planet Financial institution.


The Planet Health Organisation’s director-common, Margaret Chan, explained: “The great progress we have seen in excess of the previous two years is proof of the electrical power of partnerships and the generosity of companies that created commitments below the London Declaration.


“Together with the governments of endemic nations, we are quick approaching the aim of controlling or eliminating numerous of these ancient causes of human misery. This is a professional-bad initiative that is improving the lives of a lot more than a billion folks.”


Nonetheless, Julien Potet, neglected ailments adviser of the Médecins Sans Frontières access campaign, said that whilst they have been glad the campaign was attracting interest to some neglected conditions, others were still forgotten – such as yaws, which can lead to disfigurement and disability, however can be cured with a single dose of the antibiotic azithromycin.


WHO had struggled to get donations from a significant drug firm. Potet stated: “An additional illustration is snake bite, which is listed as quite neglected by WHO. [The drug organization] Sanofi has accomplished a excellent task of donations for sleeping sickness but have told us they have been seeking at stopping production of anti-venom for Africa.”


Donations, in MSF’s view, are not often the greatest way forward, he added, especially as small drug organizations can not often afford to make them.



Bill Gates: world need to stage up battle towards neglected tropical illnesses