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25 Temmuz 2014 Cuma

Obtaining The Way To Wellville: Modest Cities Compete To Get More healthy In Esther Dyson"s Most current Venture

Esther Dyson and her team are looking for a few good towns—five, to be precise—that want to take part in a grand experiment. Dyson, a tech investor named by Time magazine as one of the 10 most influential women in technology, wants to enlist small cities in a friendly competition to figure out how communities can become healthier places inhabited by healthier residents.


Here’s the idea: After going through a competitive selection process, five small cities or counties—each with a population of 100,000 or less—will be chosen to spend the next five years finding “The Way to Wellville,” as Dyson and her partners call the contest. So far, 10 finalists have been chosen, places like Scranton, Pennsylvania; Greater Muskegon, Michigan; Spartanburg, South Carolina; and Lake County, California. (A map showing the full list is here.)


The Way to Wellville tour stopped July 22 in Clatsop County, Oregon, where Clatsop Community Action’s food bank operates the community garden seen in the background. Last year, the community garden harvested 6,000 pounds of fresh produce that was distributed to hungry people in the area.



To run the challenge, Dyson created a small organization with the catchy, if slightly alarming, acronym of HICCup. The Health Initiative Coordinating Council, its full name, will assist the winning contestants in their journey to Wellville. Dyson will help bankroll the effort—she’s put in about $ 200,000 so far—and is part of the selection group choosing the final five. They’re now in the midst of a 10-city tour visiting each of the finalists and plan to announce the winners in mid-August.


Dyson’s team will help the chosen five raise money and provide an expert “navigator” to assist each town as they build a local local coalition by bringing many parties together—community advocates, health policy wonks, medical providers, local business leaders, finance experts—to develop and execute a health-improvement plan.


The contest will turn the five chosen communities into real-world, small-town laboratories. The hope is that by focusing on community-wide prevention and wellness efforts, each town will achieve real gains on a series of metrics that measure the health of the community and its people. Several of the 10 finalists have previous experience developing local health coalitions in conjunction with federal or private prevention grants. Overall metrics will be established at the start of the project for all five, with one individualized “wild card” metric for each community.


When it’s all over, Dyson told me, “I hope American health”—and not just the healthcare system—“will be changed. I hope there will be a visible impact that inspires people and actual, useful scientific data” that can be broadly shared.


Carrot harvest day at the community garden.

Carrot harvest day at the community garden.



The project’s idea and goals are solidly in the tradition of place-based efforts to improve local health pioneered by the Healthy Communities movement when it started some 25 years ago in Boston, Colorado, South Carolina and 20 California cities. Those efforts, which continue with support of funders like the Robert Wood Johnson Foundation and Convergence Partnership, focus on the links between the health of a community and its environment—including transportation, land use and access to healthy food and activity. Community Transformation Grants from the Centers for Disease Control and Prevention have helped local areas pursue the same kinds of local change and improvement since 2010. In fact, several of the 10 Wellville finalist cities received support from this federal program and a predecessor.


Dyson’s innovation is to take a more entrepreneurial approach that incorporates new technology and encourages collaboration with investors, as well as philanthropists and community stakeholders. For her, the concept was inspired by an idea she once heard floated to use small towns as laboratories for health innovation and improvement. Since it never came to pass, she decided—and publicly announced—she would do it herself.


“Then I had to figure out what I had gotten myself into,” she laughs. She convened a series of brainstorming meetings to develop the concept. In the process, she met and hired Rick Brush, a former Cigna Cigna health insurance executive who has spent the last several years looking at ways to create market-based incentives that lead to improvements in the health not just of individuals, but of whole communities. As HICCup’s CEO, part of his job will be to help the communities work with health insurers and investors who hope to generate revenue by reducing spending on healthcare costs.


“Our DNA is connected to the market-based approach.” Brush told me. “The business models that demonstrate an impact on producing better health at a community level are the ones that are going to succeed.”


The project has moved rapidly since the call for applications was issued April 10. Forty-two applicants submitted by the May 23 deadline; since then the six-member selection committee has narrowed the pool to 10 finalists. The five winners will be selected in mid-August after site visits to the final candidates that are now underway.


The contest will raise help each town raise its visibility, helping attract publicity and financial support. Brush estimates each town will need to raise $ 15 million to $ 50 million in cash and in-kind contributions to fund community transformation efforts. HICCup’s navigators will help them apply best practices in the areas of prevention and health-improvement and make use of cutting-edge technology.


The HICCup team will also develop three networks of partners. The first will be a “health mart” to include startups and companies like IBM IBM that are developing health apps and IT systems as well as national retailers like Walmart and Walgreens that want to “assess whether they can create a market for healthy foods,” says Brush.


A second network will help the towns attract capital and develop new kinds of sustainable financing that can pay for health-improvement efforts over the five years of the contest and beyond. One approach is social impact bonds—financing vehicles that raise money from private investors to address conditions like moldy homes or polluted air that perpetuate asthma. If the people’s health improves, reducing healthcare costs, the investors get some of the savings back as profit.



Obtaining The Way To Wellville: Modest Cities Compete To Get More healthy In Esther Dyson"s Most current Venture

30 Haziran 2014 Pazartesi

Leprosy is nevertheless current in Britain and usually misdiagnosed, say authorities

Nina Goad, a spokesperson from British Association of Dermatologists stated: “When people hear the term leprosy, they usually believe of leper colonies and references to the condition in the Bible or films like Monty Python’s Daily life of Brian.


“They are almost certainly not aware that it can still take place right here in the Uk. Diagnosis in western populations this kind of as the United kingdom is typically delayed due to the fact physicians are unaware of the disease’s presence in their country, or of its signs and symptoms.


“Dermatology is hugely underrepresented in GP training to begin with, so uncommon ailments like leprosy are seldom taught.


“Even so, early diagnosis and remedy are essential in limiting the nerve damage that triggers the numbness that can in flip lead to loss of limbs or digits.”


The condition, recognized as Hansen’s Illness, is a chronic infection by Mycobacterium leprae and Mycobacterium lepromatosis.


Despite the fact that it is not contagious, it can trigger tissue to fall off, rot away, and grow to be deformed.


The way it is passed on is by close and regular speak to amongst a contagious sufferer and a particular person who is genetically vulnerable to creating the illness.


Scientists feel that similarly to a cold, it can be passed in droplets of saliva from the nose and mouth.


The illness which dates back to 600 BC can strike decades after initial infection and lead to lesions on the skin, loss of sensation in affected areas.


Historically lepers have typically been ostracised by their families and communities, major to the setting up of leper colonies for the duration of the middle ages to quarantine individuals.


Dr Ausama Atwan, from Cardiff University explained: “Our aim is not to alarm folks unduly as leprosy is nonetheless uncommon in the United kingdom, but it is undoubtedly one thing that medical doctors need to be mindful of if they experience individuals, particularly people initially from endemic countries, with persistent or unexplained lesions, alterations to skin pigmentation and sensation.


“Leprosy might masquerade as various other skin problems, given its variety of symptoms. Due to its rarity in Europe, it may possibly very easily be misdiagnosed and consequently pose long term overall health risks for individuals if missed.


“A thorough health-related background, like elements like travel to locations in which the condition is a lot more typical, and examination of the skin and peripheral nerves, with each other with a higher degree of suspicion in men and women at risk, are essential towards diagnosis and the eventual remedy of leprosy.


“The potential prolonged incubation period need to also be borne in mind.”


In June this yr, US researchers announced that they are developing a vaccine towards the condition that is due to be trialed following 12 months.


The study will be presented to the Association of Dermatologists’ Annual Conference in Glasgow tomorrow in front of one,300 doctors.



Leprosy is nevertheless current in Britain and usually misdiagnosed, say authorities

2 Haziran 2014 Pazartesi

The most current fad in anti-selection law is a lie | Jessica Valenti

Of all the controversial concerns surrounding abortion, the newest reproductive rights battle appears fairly benign: hospital admitting privileges for abortion providers. At 1st glance, requiring medical doctors who perform abortions to be linked with a hospital that will admit their sufferers seems like a no-brainer – why not attempt to ensure a safer experience for patients? But like most anti-option measures couched in pro-female rhetoric, this legislative fight has absolutely nothing to do with creating abortions safer and almost everything to do with generating them extremely hard to acquire.


Soon after Wisconsin passed a measure final yr requiring abortion companies to have admitting privileges at hospitals, Planned Parenthood and Affiliated Health-related Companies (AMS) sued, arguing privileges are too challenging to get and that the mandate will force clinics to near. On Friday, the federal judge attached to an appeal of the law mentioned he was “troubled” in creating a decision, and urged Dr Dennis Christensen – the provider at AMS – to preserve trying to get privileges till the judge’s written choice, which is anticipated this summer time. These Targeted Regulation of Abortion Providers (Trap) laws are also sweeping statehouses, and closing abortion clinics, across the south this spring- Mississippi, Texas, Alabama and now Louisiana and Oklahoma all passed similar measures centered on admitting privileges.


Dr Willie Parker, a reproductive justice advocate and an abortion supplier in Mississippi and Alabama, says this move by the anti-decision motion is just a way for states to “gut Roe”. Faced with a country that regularly supports Roe v Wade, the US supreme court situation that gave American girls the proper to abortion, anti-choicers have resorted to a “chipping away” approach: inundating states with so several abortion restrictions that Roe is near-useless. So whilst abortion stays legal in title, all the waiting intervals, ultrasound mandates, Trap laws and consent mandates implemented by state legislatures make abortions so challenging to get that the method becomes successfully unlawful.


And when it comes to those admitting privileges so well-known between anti-selection politicians and the advocates who back them, Parker notes that less than 1% of abortion care even necessitates hospital care. “It passes the frequent sense test, but when you seem deeper, it truly is a barrier,” he informed me late final week. “Given that hospital care is practically in no way indicated, requiring it below the guise that it facilitates care is not informed by the actuality of how medicine is practiced.”


Parker also pointed out that the selection to grant admitting privileges to medical professionals is generally a perform of the company arm of the hospital, and part of what those choice-makers get into consideration is how a lot of sufferers – and how significantly funds – a medical doctor will carry in. So abortion suppliers – who almost never ever transfer individuals to hospitals – could not be ready to get privileges exactly since abortions are so risk-free. Combine that with how considerably hospitals generally loathe to get embroiled in political fights – and that some are threatened with protest and harassment by anti-selection activists – and all of a sudden it gets rather difficult for anybody who actually performs abortions to get their admitting rights in the very first spot.


The truth is that these thinly-veiled laws have absolutely nothing to do with what’s safest for females. In the extremely unusual case that a patient receiving abortion care wants hospitalization, that patient is taken to the nearest hospital emergency room. In reality, requiring companies to consider sufferers to hospitals exactly where they have privileges could mean bypassing the nearest hospital and putting the patient in danger.


The other clear indication that mandating admitting privileges has nothing at all to do with women’s health or abortion safety is that the identical movement fighting for this legislation is simultaneously attempting to strip privileges from the medical doctors that do have them. In Texas, two medical doctors have sued University Standard Hospital Dallas soon after their privileges have been out of the blue revoked when the hospital sent them a letter saying that delivering abortions constitutes “disruptive behavior” and that carrying out so damages the hospital’s status.


Nancy Northup, president of the Center for Reproductive Rights, mentioned in a press release that the doctors’ case demonstrates how “Texas has put the constitutional rights of its ladies in the hands of biased hospital administrators,” and how the care options for females in the state will continue to shrink.


Louisiana Representative Katrina Jackson says the law in her state “is about the security of ladies”. When abortion suppliers in Texas have been needed to get admitting privileges, Mark Crutcher, president of Lifestyle Dynamics, sent out postcards “warning” hospitals that “Elective abortions are not healthcare and have absolutely nothing to do with the practice of medicine.” And Mississippi Gov Phil Bryant, soon after signing his state’s bill mandating hospital privileges, explained the legislation was crucial in “defending the health and safety of females” and that he would continue “to function to make Mississippi abortion-free of charge”.


Sound familiar? “Folks need to have to connect the dots and understand that ‘women’s safety’ is the thin veneer of the real agenda to outlaw abortion,” Parker says. “The ‘safest’ abortion to them is the one that never takes place – and that is what these people suggest to do.”



The most current fad in anti-selection law is a lie | Jessica Valenti

10 Mart 2014 Pazartesi

Avoiding HIV: the most current on vaccine improvement and gene therapy

Hands holding genetic molecules. Image shot 2010. Exact date unknown.

The very likely cost of gene therapy tends to make it an unrealistic option for individuals in the creating globe. Photograph: Alamy




There has been a advancement in HIV prevention and treatment. What’s occurred?


Two groups in the US [the Aaron Diamond Aids analysis centre and the Centre for ailment handle and prevention] have shown that injection of prolonged-acting HIV drugs could totally avoid infection of monkeys. This is significant since, if it operates in people, it may be feasible to get a shot in the arm every 3 months to protect by yourself against HIV. The exact same technological innovation could be employed to treat individuals presently infected with the virus.


Will the new advances in gene therapy influence therapy in a comparable way and how do they perform?


Despite the fact that innovative, these findings are at a ‘proof of concept’ stage. Scientists had been ready to acquire massive numbers of white blood cells from infected individuals, and use gene treatment to eliminate a single of the receptors that lead to HIV infection. These cells had been then transfused back into the sufferers and remained resistant to infection. Although promising, only a tiny percentage of cells actually grew to become resistant. A lot of work will be needed to make this technique clinically effective. The very likely cost of this kind of an method in its recent format tends to make it an unrealisable option for people in the building globe. If the technological innovation progresses, this may possibly sooner or later adjust but at the moment this is an aspirational purpose.


You specialise in HIV transmission what are you operating on at the minute?


At the Imperial College London department of medication, we are operating on establishing preventive vaccines towards HIV and repurposing the use of drugs typically utilized in treatment, to avert infection. It is an fascinating time as the two fields are moving quite rapidly.


Anti-retroviral drugs support maintain infections down, but the far more they are utilised the more drug-resistance goes up. Will this new development assist get close to this problem?


Drug resistance transpires largely when patients miss taking their medicines. Prolonged-acting, injectable medicines will get about this issue as individuals won’t need to don’t forget to get tablets each day. It would also be useful for prevention as it could be administered along with injectable forms of prolonged-acting contraception.


What ought to different groups in the advancement sector do next to make the most of this new study?


This is a single of a range of new technologies that may possibly aid reduce the epidemic. To make the most of this and other emerging approaches, human trials will need to have to be accelerated. We have to be sure that any approach is risk-free, effective, inexpensive, accessible and wished by those most at danger of infection. There is no level in creating something that no person can afford or will want to use. This can only be completed by involving broad groups from the development sector to target affected communities. In the meantime, we want to encourage strategies that we know decrease transmission, which includes condom promotion and secure sex practices.


Robin Shattock is professor of mucosal infection and immunity at the department of medication, Imperial College London. Follow @FoMImperial on Twitter


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Avoiding HIV: the most current on vaccine improvement and gene therapy

4 Mart 2014 Salı

Can we afford quality healthcare in the current financial climate?

Ambulance outisde A &amp E

Crowded A&ampEs, extended waiting occasions and the trend of slightly slower emergency ambulance response, show cracks in quality. Photograph: Bethany Clarke/Getty Images




Just one particular year after the last Francis report – yet it appears a whole lot has took place. Examination by the Nuffield Believe in indicates although “top quality” has been “on the agenda” there are genuine concerns about the affect of financial constraints. Can we afford high quality?


The QualityWatch programme was set up to aid us realize what is taking place to high quality for the duration of periods of monetary constraint. A lot of our information is sourced from efficiency measures utilised inside of a support – and a lot of effort is going in to searching at what’s happening to high quality inside organisations. But we also require to look across providers too. I feel there are two places where this is specifically crucial.


The initial, is a essential focus on models of integration close to the apparent pressures on A&ampE and urgent and emergency care. Though efficiency is still much better than it was 10 many years ago, when you appear across the measures you see worrying signs of cracks.


These appear as crowded A&ampEs with prolonged waiting times, the trend of slightly slower emergency ambulance response and the continued rise in emergency admissions – particularly for some important groups like the frail elderly. Moreover this group is also made far more vulnerable by “unprecedented” reductions in social care investing.


As we, and a lot of other individuals, have observed, these changes are unlikely to be due to a single factor but are more about the broader methods of care and our capability to avoid health crises and choices to hospital and A&ampE visits.


The second location has acquired significantly less attention of late and is around the public wellness indicators – specifically the ones linked with prevention. These standard measures of population health are typically a reflection of a lot more than NHS care, but they can be slow to create alter.


Nonetheless there are some markers that are far more sensitive and want to be watched, simply because they give early warnings of likely troubles in the longer phrase. These contain indicators all around health associated behaviours this kind of as teenage conceptions, or people linked with the supporting processes about health screening and promotion.


There is also the question of overall health inequalities – which have stubbornly persisted while our common wellness improves. As money gets tighter it truly is more and more important that we watch cautiously to make sure that economies do not adversely have an effect on the good quality of services and the nicely getting of disadvantaged subgroups of the population.


Each these concerns suggest the need to collate information, occasionally from providers, at a population level. Exactly where information like this was once analysed by main care trusts – it now resides in between 3 new organisational types – clinical commissioning groups, commissioning help units, health and wellbeing boards and Public Overall health England.


But these are difficult occasions, especially for those charged with establishing this neighborhood viewpoint, and it is critical that these bodies are supported in taking these population based views.


This indicates producing data accessible across a locality, and having the capability and tools to combine info from companies and major and neighborhood care services directed at the exact same population.


One instance is currently being able to accessibility anonymised data that link care episodes for a defined population, and capture the essential occasions in terms of people’s wellness, wellbeing and service use (such as the kind of details that can be gleaned from initiatives such as care.data). For illustration we need to have to know, not just how effectively folks recover from a hip fracture, but how effectively regional preventive approaches are lowering the prevalence of hip fracture.


So yes we do have to enhance the way we look at good quality inside organisations – and yes we do have to fill in the holes in our data sets – but we also need to invest in comprehending the info that spans solutions. This perspective is going to be vital if the fledgling designs of integrated care are to be effective, and if health and nearby authorities are to commission greater quality outcomes for the whole neighborhood.


Martin Bardsley is the director of investigation at Nuffield Believe in the Guardian Healthcare Professionals Network is media companion for the trust’s Well being Policy Summit on March 6 and seven.


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Can we afford quality healthcare in the current financial climate?