Substances in Cinnamon Affect Breast Cancer Cells

The Egyptians, the Chinese and ancient Europeans used to use the brown bark of the cinnamon tree for its anti-bacterial, anti-fungal, anti-inflammatory and even food preservation properties. Recent studies have shown how cinnamon can have a direct effect on many kinds of cancer, including breast cancer.

What is in cinnamon that makes it such a cancer healer?

Cinnamon contains an extraordinary amount of cancer-healing substances within it; cinnamaldehyde is probably the most studied substance within this warming herb. It has demonstrated its antiproliferative (anti-cancer) properties in quite a few studies, especially when it comes to lung and colon cancer. A 2015 study conducted by the University of Arizona found that cinnamaldehyde in Cassia cinnamon suppressed colorectal cancer metastasis through inhibiting inflammatory responses which help cancer cells to grow. Other studies have found cinnamaldehyde to have an effect on liver cancer cells. Studies have also shown that cinnamaldehyde prohibits the mechanisms of VEGF, or vascular endothelial growth factor, a major contributor to cancer cell growth.

In addition, cinnamon contains the phenylpropene, eugenol, which has proven its healing abilities on breast cancer cells. According to a 2013 study conducted by the King Faisal Specialist Hospital and Research Center in Saudi Arabia, the eugenol in cinnamon inhibited the substance Survivin in various kinds of breast cancer cell lines. Survivin is produced by cancer cells to help them avoid normally-occurring cellular death. Essential oils of clary sage, holy basil and clove also contain high levels of eugenol.

Finally, cinnamon contains the phytoestrogen coumarin, which may also have a positive effect on breast cancer growth and metastasis. Contrary to popular belief, naturally-occurring phytoestrogens do not need to be avoided when one is healing or wanting to prevent breast cancer. In fact, the phytoestrogens found in flax and pumpkin seeds, as well as in cinnamon, provide mild forms of estrogen which can help reduce estrogen-positive breast cancer tumors or prevent them from ever developing in the first place.

Phytoestrogens attach to cellular receptors within the mammary glands, replacing more “aggressive” xenoestrogens (or chemically-created estrogen “mimics”) with milder, naturally-sourced mimics.  Xenoestrogens are the main culprit in the vast majority of estrogen-positive breast cancers diagnosed each year.

Going along with cinnamaldehyde and eugenol’s cancer-culling effect are the detoxification properties of fiber, calcium and manganese that cinnamon provides. Fiber and key essential minerals can add to cancer prevention, especially from colon cancer.

Other Healing Properties of Cinnamon

 The properties found in cinnamon have other benefits too. As a super-antioxidant, cinnamaldehyde has the ability to chelate metals from the body. A comprehensive review conducted by the MD Anderson Cancer Center in Texas also found that the nutraceuticals in cinnamon were neuroprotectant and should be studied further for its benefits for Parkinson’s and Alzheimer’s patients

“Research over the last 10 years has indicated that nutraceuticals derived from such spices as turmeric, red pepper, black pepper, licorice, clove, ginger, garlic, coriander, and cinnamon target inflammatory pathways, thereby may prevent neurodegenerative diseases,” the report stated.

Finally, cinnamon is a known blood-glucose stabilizer, as demonstrated by several studies. Cinnamon supplementation is often recommended by natural health practitioners for help with Type 2 diabetes.

Cinnamon has been a healing herb in Asia and elsewhere for thousands of years and new scientific evidence is proving its cancer-healing and prevention power along several fronts. Now every time you sprinkle some on this delicious spice on a warm beverage or food, you will know that you are heading in the right direction and towards a healthy, vibrant, cancer-free life!

Dr. Veronique Desaulniers, better known as Dr. V, is the founder of  the 7 Essentials System ™, a step-by-step guide that teaches you exactly how to prevent and heal Breast Cancer naturally. To get your FREE 7-Day Mini e-Course and to receive her weekly action steps and inspiring articles on the power of Natural Medicine, visit her at BreastCancerConqueror.com

Substances in Cinnamon Affect Breast Cancer Cells

US bakery giant Panera to swear off artificial substances by 2016

Panera says it will get rid of artificial colors, flavors, sweeteners and preservatives from its foods by 2016, a reflection of the developing distaste people are exhibiting for this kind of elements.

The chain of bakery cafes, which has about 1,800 US areas, is producing the pledge as element of a “Foods Policy” it is unveiling Tuesday that outlines its dedication to “clean” and “simple” substances.

The announcement comes at a time when Panera Bread Co is facing slowing sales growth and functioning to jumpstart its organization through a selection of indicates, this kind of as revamping the occasionally complicated way folks order and get foods and switching baking hours to the daytime to develop a homier truly feel in cafes.

The unveiling of Panera’s sweeping “Meals Policy” also underscores how positioning food items as natural has turn out to be a advertising benefit, irrespective of regardless of whether it brings any dietary positive aspects. Element of the attraction for consumers is that they come to feel far better about what they’re consuming, often because they don’t truly feel as guilty about how several calories they are consuming.

Chipotle, for instance, has acquired in reputation in portion by portraying itself as a a lot more wholesome different to classic rapidly-food chains like McDonald’s. Even Subway not too long ago said it would quit making use of azodicarbonamide in its breads. The ingredient was dubbed the “yoga mat” chemical right after a petition by Vani Hari, who runs FoodBabe.com, noted it was utilized to make yoga mats.

Still, declaring food items as getting organic or free of charge of artificial substances has the potential to invite criticism and even legal troubles. A lawsuit filed in November, for instance, alleges that Entire Meals Marketplace employs a “spectacular array” of artificial substances in some of its shop-brand goods, despite the grocer’s promise that the items have “nothing at all artificial.”

Panera also is not swearing off genetically modified components, yet another problem that is gaining consideration in certain circles. As opposed to Chipotle, which says its menu will quickly be free of charge of GMOs, Panera makes use of as well numerous various elements to be ready to make that declare. And neither chain has any ideas to end promoting fountain sodas from Coca-Cola and PepsiCo, even even though the drinks are sweetened with substantial fructose corn syrup.

As for the rest of its menu, Panera says it is about halfway by means of the removal of artificial elements. It’s nevertheless looking for techniques to removes the artificial colors used in its bakery icings, for instance, and is testing a smoked ham in select markets that isn’t going to use artificial preservatives.

“We made a decision it was time to put all this into a clear and concise policy,” Ron Shaich, Panera’s founder and CEO, explained in an interview.

Ten years in the past, for instance, Panera announced that it would use chicken raised without having antibiotics, a move Shaich said assisted drastically drive product sales.

Panera’s new policy also states the chain’s commitment to “transparency,” that means it will make it straightforward for individuals to see the components and nutritional content material of its meals. It also says it will work to have a “good affect” on the meals method, this kind of as by supporting North American suppliers every time feasible.

Regardless of whether the new policy assists entice much more clients is yet to be seen.

Last yr, Panera’s sales rose 2.six% at firm-owned locations open at least a yr. That was down from 6.5% in 2012 and four.9 % in 2011.

This yr, the St Louis-primarily based firm is forecasting product sales development of two to 3.five%.

US bakery giant Panera to swear off artificial substances by 2016

Manmade or normal, they"re all chemical substances | Dr Mark Lorch

Chemical substances are negative, right? Otherwise why would so many purveyors of all issues wholesome proudly proclaim their goods to be “chemical-free of charge” and why would phrases such as “it’s chock complete of chemicals” be so generally used to imply anything is unnatural and as a result inherently hazardous?

On one particular level these phrases are meaningless – after all, chemical substances are all over the place, in almost everything. From the air that we breathe to the drugs we pop, it really is all chemical substances. Conversely, several would argue (the Marketing Specifications Agency included) that we all know perfectly properly what “chemical-cost-free” implies and individuals who rail against the absurdity of the phrase are just currently being pedantic. Even the Oxford Dictionary defines a chemical as “a distinct compound or substance, especially 1 which has been artificially prepared or purified.”

So “chemical-totally free” goods are adhering to a recognised usage.

But pedantry and definition aren’t actually the point. The level is that each and every time anti-chemical slogans are used folks are being misinformed. The implication is usually that the terms “chemical” and “poison” are interchangeable. This is a perception that permeates our subconscious to the extent that chemists themselves have been guilty of precisely the exact same lazy language.

As a consequence of this frequent usage of “chemical compounds” the total subject has been tainted with unpleasant connotations. And although physics and biology have their celebrity scientists extolling the wonders of bosons, bugs and big bangs, chemists are left floundering in their wake or are left entirely unrepresented in the mainstream media (where’s the Guardian’s chemistry site?).

This is all despite the modern globe obtaining been created on the innovations of chemists. For illustration, most of the world’s population is sustained by the innovations of 1 of them. Fritz Haber invented a means to turn the nitrogen in the air into valuable agricultural fertiliser (forty% of the nitrogen in you comes from Haber’s reaction). Meanwhile the chemists who artificially ready or purified antibiotics are responsible for a therapy that saves much more lives than any other healthcare intervention.

All these arguments are trotted out by chemistry bloggers on a typical basis, but these writers are only preaching to the converted. The very good information is that on Monday the campaign group Sense about Science joined the discussion with the publication of a guidebook entitled Generating Sense of Chemical Stories. Sense about Science is a respected charitable organisation that “equips men and women to make sense of scientific and health-related claims in public discussion”. In quick, it facilitates discussions in between concerned/interested groups and related authorities.

‘A typical misconception is that all manmade chemical substances are hazardous, and all organic chemical substances are very good for us. However, many all-natural chemicals are just as damaging to human health, if not more so.’ Photograph: Compound Curiosity/Sense About Science

The aim of its guide is to bridge the disconnect in between the life-style view (and well-liked definition) of chemical compounds and the realities of how chemistry is utilized to sustain the contemporary world. The guidebook does this by tackling common misconceptions about chemistry.

A crucial misconception is that normal chemicals are by some means safer than manmade ones. The wrongheadedness of this is nicely illustrated by a pair of infographics (above) developed by Sense About Science that really don’t shy away from admitting synthetic chemical substances are usually toxic, but also make it clear that regardless of whether a chemical is naturally happening or manmade tells us precisely nothing about its toxicity.

Not only that, but the place dangerous chemical substances do occur (be that in potatoes or lethal injections) the dose is the genuinely critical point to think about.

Generating Sense of Chemical Stories is being promoted to the public, journalists, life style press and policymakers. It, along with the infographics, are freely available to download from Sense about Science, or if you choose a hard copy (or a box complete of them) electronic mail enquiries@senseaboutscience.org or call 020 7490 9590 with your make contact with information.

Buy some and spread the word: chemicals are good for you!

Mark Lorch is a senior lecturer in chemistry at the University of Hull. He blogs at www.chemistry-weblog.com and tweets as @sci_ents

Manmade or normal, they"re all chemical substances | Dr Mark Lorch

Chemical substances In Your Breath Could Reveal Lung Cancer, New Investigation Says

A straightforward breath check for lung cancer acquired a phase closer to reality right now with analysis exhibiting that specific compounds in the breath can indicate the presence or absence of lung cancer. Findings presented to the Society of Thoracic Surgeons 50th yearly meeting showed that large-tech sensors can detect particular compounds in the breath released by lung cancer cells.

Michael Bousamra, M.D. and a team of researchers from the University of Louisville designed a silicone microprocessor and mass spectrometer that showed 95-% accuracy in detecting certain volatile organic compounds (VOCs) connected with lung cancer. Named carbonyls, and more specifically aldehydes and ketones, these compounds produced by the body and can present a variety of metabolic signature for lung cancer and other sorts of cancer.

Bousamra and colleagues gave the breath check to individuals who currently had suspicious tumors that had been detected by CT scans. Then they matched the breathalyzer findings with biopsy and clinical data. For sufferers whose breath contained elevated levels of three or four VOCs related with cancer, the breath check was 95 percent precise in predicting their tumors would flip out to be malignant, the researchers mentioned.

The opposite also proved true. When participants’ breath did not incorporate the cancer-distinct carbonyls, the test was 80 % correct in predicting that their tumors would turn out to be benign.

The researchers cautioned that their information are preliminary and have yet to be published in a peer-reviewed journal. Nevertheless, there’s ample proof to help the thought that cancer cells release certain natural compounds in the breath that can indicate the presence of a tumor.

For example, in 2012, a staff of researchers from the Winship Cancer Institute at Emory University presented findings to the American Society of Clinical Oncology (ASCO), published in the Journal of Clinical Oncology, exhibiting that 75 specific VOCs have been considerably different in the breath of individuals with lung cancer vs. people who have been cancer-totally free. The Emory University researchers employed a device developed by the Georgia Tech Research Institute.

A “biosignature” of compounds in the breath may reveal lung cancer, research displays (photograph: public domain)

Yet another examine published in 2012 identified colon cancer with more than 80-% accuracy using 15 previously identified VOCs.

In reality, the race to best and demonstrate a breath check for cancer is on all around the nation, with many analysis teams functioning to recognize cancer-specific patterns of VOCs and to develop devices delicate adequate to accurately measure their presence.

And no wonder. Lung cancer is the deadliest cancer of all, killing more people than breast, prostate and colon cancer mixed, according to the American Lung Association. A single of the principal reasons lung cancer is so deadly is that it’s typically caught at a late stage, when it’s currently begun to spread, or metastasize. Stage I lung cancer has a 70-% remedy price, but by stage III or later on fewer than 25 percent of situations can be cured. Hence the importance of establishing tests that can detect lung tumors early.

Mountain See, California-based Metabolomx may possibly be the furthest along in the race to carry a cancer breath check to marketplace. The company’s colorimetric sensor, which detects and measures VOCs employing 36 different chemically reactive colorants, is being examined in trials at the Cleveland Clinic’s Respiratory Institute.

Utilizing Metabolomx’s sensor technology, Peter Mazzone, MD, director of the Institute’s lung cancer program, published study and presented findings at the American School of Chest Physicians Yearly Meeting (CHEST 2013) exhibiting that VOCs in exhaled breath could give a “metabolic biosignature” that was 75-% precise in identifying compounds linked with lung tumors.

Metabolomx reviews that the business has launched new trials in partnership with the Cleveland Clinic employing a up coming-generation sensor that is one hundred instances much more accurate.

Chemical substances In Your Breath Could Reveal Lung Cancer, New Investigation Says