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10 Eylül 2016 Cumartesi

Corneas, heart and pancreas: the organs that we are reluctant to donate

In Organ Donation Week, it’s heartening to see that the number of people consenting to have their organs used after their death is at its highest-ever level. There were almost 22.5 million registrants on the donor register as of 31 March – up 6.6% on the previous year.


While the majority of those registered have given consent for all their organs and tissues to be donated, one in eight are “restricted donors” – people who have registered, but state that they don’t want to donate specific body parts.


Registrants on the organ donor list since 2007
Registrants on the organ donor list since 2007.

If you are squeamish about giving up your eyes even in death, you are not alone. NHS figures show that the vast majority of those who opt out – almost 90% of those who choose not to donate, and 10.7% of the whole register – do so because they don’t want to give their corneas.


There is a shortage of cornea donors in the UK. In the year to 31 March 2015, almost 3,780 cornea transplants were recorded on the UK transplant registry. However, while the NHS would require an average of 10 donations a day to meet demand, it only receives on average seven viable donations per day.


Organs most often restricted on the donor register

Among the restricted donors, a much smaller proportion opted out of donating their heart, pancreas, lungs, liver or kidneys.


Although people of all ages are eligible for organ donor registration, the highest proportion of donors are in their late teens and 20s: people aged between 16 and 30 make up 43% of the current register.


Registrants by age group
Organ donor registrants by age group.

While a higher proportion of women aged between 16 and 30 are registered than men in the same age category, the reverse is the case in the older age groups.


All the figures cited here exclude the 177,204 people in the UK who have specifically asked not to become an organ donor when they die.


Registrants by gender across age groups
Registrants across age groups by gender.

organdonation.nhs.uk



Corneas, heart and pancreas: the organs that we are reluctant to donate

16 Haziran 2014 Pazartesi

"Bionic pancreas" passes check to help management diabetes

Lead researcher Dr Roman Hovorka, from Cambridge University, explained: “The benefit of a ‘closed-loop’ technique like this one particular is the capability to fine tune insulin delivery to account for variations in overnight insulin requirements.


“The system was able to adapt and safely cope with these variations to achieve far more constant glucose control. Now that we’ve examined the method at several centres, we can see that its rewards apply to a wide selection of folks.


“A large-scale clinical trial of the artificial pancreas will now be the up coming phase in assisting to translate these fascinating findings into an end item that will help to transform the management of Kind 1 diabetes by achieving steady glucose ranges and reducing the risk of blood glucose levels falling dangerously reduced in the course of the night. This kind of a item may possibly be viable with present technology.”


A equivalent smartphone-linked artificial pancreas has also been created by American scientists. The mechanical device, worn outdoors the entire body, includes an iPhone wired to a steady glucose monitor.


The gadget, produced at Massachusetts Basic Hospital and Boston University, has passed a actual-world test, continuously monitoring blood sugar and immediately offering insulin as essential


All around 300,000 individuals in the Uk endure from Type 1 diabetes, which is an autoimmune illness unlike the a lot much more common Type 2 issue.


The disease destroys insulin-producing islet cells in the pancreas, creating it necessary to have typical injections of the hormone.


Findings from the Uk examine had been presented at the American Diabetes Association’s annual meeting in San Francisco and published in The Lancet Diabetes &amp Endocrinology journal.


Dr Alasdair Rankin, director of investigation at Diabetes United kingdom, stated: “The prospective health positive aspects of this could be tremendous. At the moment, folks with Sort one diabetes are in excess of twice as probably to die in any offered yr as somebody of the identical age who does not have the condition. That is a tragic actuality that the artificial pancreas has the possible to adjust.”



"Bionic pancreas" passes check to help management diabetes