“Silent” etiketine sahip kayıtlar gösteriliyor. Tüm kayıtları göster
“Silent” etiketine sahip kayıtlar gösteriliyor. Tüm kayıtları göster

9 Ağustos 2016 Salı

Inflammation – The Silent Killer

Were you aware that inflammation in the body is the link between debilitating conditions like arthritis, cancer, heart disease, and even Alzheimer’s?


It is also thought to be one of the key causes of the visible signs of aging. In the wellness sphere, you hear the word inflammation a lot.


When you reduce the inflammation in the body, you not only look and feel your best, but you lower your risk for chronic disease. Reducing inflammation can seriously turn back the clock.


What is Inflammation?


When your body responds to stress, it creates inflammation. The cause can be diet, environment and/or lifestyle. Take for example when you catch a cold. You’re going to experience inflammation in the form of a fever because your body is heating up to kill the pesky virus. This is a good kind of inflammation because it is helping your body.


There’s a modern epidemic of chronic, low-grade inflammation that can destroy the balance in your body. When you’re experiencing the chronic inflammation response, you’re more susceptible to disease and premature aging.


What Causes Inflammation?


There are several factors that can cause inflammation in your body.


One main cause is low-grade bacterial, viral, and fungal infections in the bloodstream and organs. This can affect your stomach and gastro-intestinal tract. Take for example H pylori, a bacteria in the stomach that contributes to inflammation and the development of ulcers. 50% of adults over 60 years old and 20% of adults under 40 have it, but inflammation is caused by so much more than just pathogenic organisms.


Some Other Causes of Inflammation


You can have symptoms from low-grade food allergies and food sensitivities. When there is an imbalance of bacteria and fungi in your gastrointestinal system, called dysbiosis, then your immune system will overreact with adverse symptoms.


Stress in the form of constant psychological, emotional, and physical stress raises your cortisol level and leads to inflammation.


Environmental toxins like pollution in the water, air, food, and even toxic metals like mercury will contribute to inflammation and can even lead to diseases like endometriosis and cancer.


When you have a poor diet with too much of the bad fat, sugar or protein it can lead to constant dehydration. The consumption of oils from grains, such as corn oil, canola, peanut oil and on, creates an imbalance between omega 6 and omega 3. Too much omega 6 will cause inflammation. The best fats are coconut oil, olive oil, butter from grass fed cows, organic butter and ghee.


Also, the consumption of too many sodas, caffeine, inactivity, and lack of sleep will all cause inflammation in the body as well.


What are the Lasting Effects of Inflammation?


  • Arthritis

  • Heart Disease

  • Osteoporosis

  • Chronic Pain

  • Psoriasis

  • Acne

  • Weight gain

  • Obesity

  • Acid Reflux

  • Visible signs of aging

  • Cancer

  • Bacterial, fungal, and viral infections

  • Bronchitis

  • Diabetes

  • High blood pressure

  • Candida

  • Urinary tract infections

How Can You Reduce Inflammation?


This is a controversial topic, and everybody is going to give you a different answer. You need to follow a balanced diet that limits sugar and salt (table salt NaCl) while feeding yourself key nutrients in a way that supports your health and vitality. Also, increase your mineral intake and eat anti-inflammatory foods such as vegetables (excluding the nightshades), fish, eggs, meat and some fruits especially berries.
Be conscious of your stress levels and seek to reduce it. Make sure you’re getting plenty of sleep and get a little sunshine. Vitamin D can effectively reduce inflammation, and you get it from sunlight. If it’s in the winter, then be sure to take Vitamin D in the form of supplements.


5 Tips to Reduce Inflammation


1. Eat a whole food diet: some of the most inflammatory foods you’ll find include refined sugar, grains, wheat, flour, processed food, junk food, sodas, alcoholic beverages, chips and ice cream. That’s why going with a diet of whole foods and choosing to eat wild fish abundantly as well as grass fed ( not grain fed) animals will help reduce the inflammation. When you add more of these foods, you’re filling your body up with vitamins, minerals, and cancer-fighting phytochemical compounds, as well as antioxidants and fiber.


2. Pay attention to gut health: Did you know that your gut is 60-70 percent of your immune system? That makes it the perfect place to reduce that inflammation. When your gut is in bad shape your immune system falls into serious trouble. The best way to begin is by taking a daily probiotic, but be sure that it is of the highest quality. Eating prebiotics food such as cultured sauerkraut, brussel sprout, artichokes, yogurt, kimchi, pickled vegetables will create a sort of nesting area in your gut where probiotics can flourish.


3. Become aware of food sensitivities and chronic infections: If you’re battling with food sensitivities or chronic infections, then your body is over-compensating to cope with it everyday life. Inflammation is created on a daily basis by these offenders. That’s why you also need to make sure that gluten, soy, dairy, and eggs aren’t a problem for you. The best way to identify a problem is through a blood test or elimination diet. Don’t eat a certain food for 21 days, then eat plenty of it in one day. If you are doing well in the next 3 days, it’s ok to eat this food again. If you have a negative response stay away from it.


4. Get more rest and relaxation: Your body is constantly working hard to repair and restore itself, and this mostly happens while you sleep. Doctors recommend that you get seven to eight hours of sleep each night. When you’re not getting enough, then your immune system is going to suffer, and that is going to lead to more inflammation.


Stress is just another component that adds to a lack of sleep.
When you’re stressed all the time you’re producing more of the hormone cortisol, and this leads to serious inflammation. You can, therefore, reduce chronic inflammation by focusing on stress reduction, either through more sleep, yoga, meditation, less technology, or even just taking a vacation. Sometimes, you need to take a break. Also take a look at the people around you and the toxic effect they could have on you.


5. Reduce the toxins in your food, personal care products, and home. When you are absorbing too many toxins from various products throughout the day, your body’s alarm system is going to go off. You want to cut down on your exposure by eating organic products and drinking filtered water as much as possible while also choosing non-toxic personal care and cleaning products. The key is to go as natural as possible, so look for those ingredients that come from nature.


The Bottom Line


Inflammation can kill you. There’s no other way to say it. If you’re feeling the signs of inflammation or seeing them in the mirror, then it’s time to do something about it. Take small steps each day to lessen your toxic load, relax a bit, get some sleep, and you’re going to feel like a different person.


References:


http://www.ncbi.nlm.nih.gov/pubmed/22126533


Scandinavian Journal of Gastroenterology 2012 Jan;47(1):49-58


http://journals.cambridge.org/action/displayAbstract;jsessionid=C2160A7957DC4D4A183D879E206D89D4.journals?aid=9968201&fileId=S0007114515002093



Inflammation – The Silent Killer

21 Ağustos 2015 Cuma

Antibiotic resistance: the race to cease the "silent tsunami" dealing with present day medication

Off the coast of California, almost 20,000 feet under the surface of the Pacific Ocean, scientists from the San Diego Institute of Oceaneography are collecting samples of marine daily life from the ocean floor. At initial glance, these little clumps of sediment may seem nothing unique, but the micro-organisms which lie within might 1 day provide an response to one particular of the most urgent troubles in modern healthcare: the global antibiotic resistance pandemic.


To place the scale of the problem in perspective: the Ebola epidemic in West Africa captured the headlines in 2014, and in total the virus accounted for just above eleven,000 fatalities, producing it as the most devastating outbreak of the virus in history. Recent estimates area the annual quantity of deaths from antibiotic resistant bacteria at about 700,000 globally. Except if things alter this figure is predicted to rise to ten million by 2050, with increasing numbers of bacteria presently fully resistant to every clinical antibiotic obtainable.


Speaking at the current Uppsala Wellness Summit, Professor Otto Vehicles described resistance to antibiotics as “a silent tsunami, crumbling down the pillars upon which modern day medication is constructed.” Vehicles, who has spent decades campaigning for awareness on the topic, describes the problem as one particular of complacency. Although antibiotic consumption has increased by 36% in the past decade, no new courses of these medication have been identified since the 1980s.


In June, the Planet Health Organisation unveiled a global action program to tackle antibiotic resistance. One of the stated aims is to have a whole new class of antibiotics in development by 2019.


Associated: The hunt is on for new antibiotics | Jenny Rohn


But is this actually feasible? To understand the problems, it’s essential to appear at how bacteria turn into resistant in the 1st place.


“The most common way this occurs is via the acquisition of genes from other resistant bacteria,” says Gerry Wright, a chemical biologist at McMaster University in Ontario, Canada. “Bacteria are quite promiscuous and the most surprising issue we’ve realised above the previous 60 many years is just how swiftly this gene sharing happens. They typically obtain these resistance genes in packages, giving them resistance to numerous antibiotics at the exact same time, and that’s a major problem in hospitals. Resistance also develops through chance mutations in the course of DNA copying when bacteria reproduce. This is believed to be how bacteria became resistant to rifampin, a drug utilized to treat tuberculosis.”


At the molecular level, such mutations can stop an antibiotic getting into the bacteria cell at all, altering the target molecules so that they do not bind to the antibiotic anymore, or enhancing the efficiency of efflux mechanisms inside of the bacteria which permit it to merely pump a drug back out once more. Certain genes, if acquired, can actively degrade antibiotics, limiting their effectiveness once they’ve entered the cell.


In purchase to discover brand new medicines capable of destroying these mutant bacteria, many scientists are turning back to nature. At the University College London College of Pharmacy, Simon Gibbons is searching at the chemical compounds which give specified plants their antiseptic properties.


“Instead of just focusing on killing resistant bacteria, we’re also looking at ways of altering them to make them susceptible once more,” he says. “We have a couple of projects hunting at chemicals which can inhibit antibiotic efflux in bacteria, and other molecules which can inhibit the transfer of plasmids. Plasmids are small DNA molecules which spread antibiotic resistant genes amongst bacteria.”


Gibbons is monitoring a clinical trial hunting at a compound discovered in bearberries. This chemical is utilised to deal with cystitis, an infection triggered by E.coli bacteria, by either killing them or avoiding them binding to the urinary tract. Scientists are interested in no matter whether it is just as effective at dealing with other microbes.


Related: Anglo-Saxon antibiotics are just the begin | Vanessa Heggie


Even so, not absolutely everyone is convinced that plants are the most probably source of compounds capable of dealing with the world’s most virulent bacteria. “We do not have a lot of plant-derived anti-bacterial agents due to the fact of the evolution scale,” says Richard Lee, a researcher at St. Jude Children’s Study Hospital in Memphis. “Plants evolve slowly although bacteria are the actual opposite, so plants have a tendency to use non-particular approaches to fight bacteria which are tougher to translate into human therapeutics.”


In excess of the previous 80 years, the primary focal level of the search for new antibiotics has been soil microbes, and the variety of substances they create to destroy each other as element of their ongoing chemical warfare. But until not too long ago, we haven’t been specially adept at trying to keep them alive in the lab for lengthy enough to get their weapons for our personal use.


Final year, scientists in the US and Germany developed a novel technique which led to the discovery of a substance referred to as teixobactin, which they believe has the likely to turn into the very first new antibiotic given that 1987. Teixobactin has the ability to destroy some of the most dangerous drug-resistant bacteria, this kind of as MRSA, and has a extremely low prospective for the advancement of resistance – but it is ineffective towards the most difficult-to-deal with family of all: gram-unfavorable bacteria. These bacteria create resistance exceptionally speedily due to their speedy DNA sharing, which has noticed them evolve an further protective cell membrane and sophisticated efflux.


To target them, scientists are turning to daily life in some of the most far-flung corners of the planet. Organisms residing thousands of feet beneath the ocean surface have evolved their own exclusive techniques of defending themselves towards microbes in excess of millions of many years, most of which are still unknown. A compound referred to as anthracimycin, developed by a distinct bacterium living in the depths of the Pacific, has demonstrated possible but finding this kind of compounds is just a little part of the challenge. The largest problem is finding individuals which are not toxic to people. “Bacteria, humans and all residing creatures, share the same biochemical mechanisms that are essential to daily life,” Wright says. “But these are usually the items that antibiotics target. A single way to kill a bacterium is to punch a hole in its membrane, but you need to have to locate some thing that selectively punches holes in bacteria and not human cells.”


Gibbons feels the WHO’s 2019 deadline is unrealistic. “There’s a good deal of operate from easy testing to security testing, and then animal designs involving mice or rabbits, before you even feel about a clinical trial. And you have to demonstrate that you can generate sufficient of the substance itself. So I doubt we’ll see any new lessons of antibiotics till 2021 or 2022 at the quite least.”


Associated: Fighting bugs with bugs: this time it is personal | Jenny Rohn


Due to such troubles, other people are alternatively searching at redesigning outdated, discarded antibiotics to enhance their stability and effectiveness. Some have been originally abandoned because they only worked on a small handful of bacteria, but now it’s thought that a range of far more narrow spectrum treatment options could be a greater way to avoid driving resistance.


Lee is presently studying spectinomycin, an antibiotic launched in the 1960s to treat gonorrhoea, ahead of becoming cast aside as it only worked in enormous doses. He believes that a remodelled version has the possible to operate well towards a variety of respiratory tract infections and sexually transmitted illnesses.


“The drug has often been very secure, and fifty years on we now know its crystal framework,” he says. “So we can exploit that along with all the outdated expertise from the pharmaceutical organizations who experimented with to produce it in the 1980s, to increase its design and aid it accessibility the target bacteria much more effectively.”


Of program, some bacteria will ultimately grow to be resistant to spectinomycin and other outdated antibiotics, but Lee believes that it is feasible to style these medication so this comes at an evolutionary expense to the bacteria.


“Because of how they work, some antibiotics are just more difficult for bacteria to produce resistance against,” he says. “And while mutated bacteria might be able to evade the drug, they could not be capable to survive as nicely and for as prolonged. So you could become contaminated but it won’t be as virulent and threatening.”


But establishing a new product from scratch or even rewiring an previous 1 comes with significant charges and challenges, and so there are many scientists focusing exclusively on approaches to make our present antibiotics beneficial once much more towards resistant bacteria. 1 popular idea is combination therapy – combining several medicines together to kind a cocktail mix which is the two a lot more potent and hard to evade.


“Over the previous decade we’ve located that particular genes vital for the life of the bacterium, interact with a number of other genes in the cell in a complicated internet-like vogue, significantly like pages on the world wide web,” Wright says.


Associated: Resistance isn’t futile – how to tackle drug-resistant superbugs


“So our notion was, if we combine antibiotics with other molecules and use people combinations to target this internet in various random fashions, possibly we can unexpectedly enhance antibiotic exercise or conquer bacterial resistance in new approaches?”


Such random screening required vast numbers of drug combinations to be tried and tested, a thankless needle-in-a-haystack process which would have taken many years of labour in decades gone by. But with 21st century robotics technological innovation, Wright and his colleague Eric Brown are capable to display 1000′s in a mere afternoon.


There can still be sudden drawbacks as it is usually challenging to match the publicity of two medication at the site of infection to see the wanted effect.. Wright and Brown thought they’d struck gold with a mixture of the antibiotic tetracycline with a drug referred to as imodium, employed to treat diarrhoea. Imodium enhanced tetracycline’s ability to penetrate bacteria, but more testing showed this only worked in the gut, limiting its usefulness.


“The different is to have a single drug that concurrently hits a number of , frequently relevant bacterial targets generating resistance tougher to produce,” Lee says. “This is a serendipitous technique applied by several at the moment successful antibacterial agents including fluoroquinolones and beta-lactam antibiotics. But from a de novo discovery angle this is technically significantly tougher to do.”


As a result, some really feel the right combinations of drugs have main benefits when it comes to creating viable products. Provided that the individual medicines themselves are known to be protected, and can be produced in large quantities at a realistic price, the path from lab to clinic ought to, in theory, be much quicker and significantly less high-priced.


Wright believes blend therapy is the primary way forward, just as combinations of antiviral medication proved to be the way to handle HIV. “With multiple molecules, bacteria often have to produce resistance to every a single. And with 3 or even four molecules with each other, there is significantly less and much less chance of this in fact happening.”



Antibiotic resistance: the race to cease the "silent tsunami" dealing with present day medication

13 Temmuz 2014 Pazar

Silent, not deadly how farts remedy conditions | Dean Burnett

It appears like it was only final week that a study by the University of Exeter exposed that smelling farts cures all manner of fatal illnesses, which lead to a lot of media coverage about the healing properties of nether-region emissions.


Some cynical varieties experimented with to fight this, metaphorically lifting the duvet from the developing cloud of excitement. Positive, the actual research was far much more complicated, and did not especially reference farts, just hydrogen sulphide, a gas developed by all-natural bodily processes that provides flatulence its unpleasant odour. The examine claimed that targeted delivery of compound called AP39 causes a lot more hydrogen sulphide to be produced by an ailing cell, and hydrogen sulphide in little doses can prove protective to the cell’s mitochondria, which supplies the cell’s power and is usually damaged by conditions. Hydrogen sulphide avoiding this mitochondrial damage as a result can help cells resist the progression of several diseases.


Of program, for a lot of in the media, “hydrogen sulphide delivery assists prevent condition damage in cells in certain condition models” will constantly be trumped by “farts cure cancer” when it comes to headlines. But, for after, it turned out that the wild extrapolations had been true, and smelling farts really did remedy key illnesses. And as 1 may anticipate, the consequences of this were sudden, unpleasant, and lingered for a lengthy time afterwards.


First of all, a good deal of the underlying science had to be re-written. It was broadly believed that inhalation of high concentrations of hydrogen sulphide was very hazardous to well being, not advantageous. It was also believed that smelling a fart simply meant the component gases entered the lungs and were largely just exhaled again, not absorbed effectively and delivered to diseased cells.


A lot of scientists also wondered why this phenomenon hadn’t been observed before now, thinking about that the regular person is supposedly farts about 14 instances per day but there have constantly been a lot of sick individuals close to in spite of continuous publicity to these human emissions. The clear counter to this argument is that, without having the healing properties of flatulence, sickness costs could be considerably greater than they are. On best of this, studies exposed that men and women hardly ever break wind around the terminally sick, due to awkwardness and worry of saying some thing insensitive resulting in elevated “clenching” of the related sphincters.


When the existence-sustaining properties of flatulence have been extensively identified, there have been a lot of social consequences. Individuals who openly farted about others have been no longer taken care of with disdain but with grudging respect. But contrastingly, farting misplaced a good deal of its humorous associations, as individuals came to see a fart becoming made for comedic effect as a fart that could now not be utilised to save a existence, as if the dispenser had just poured a litre of blood down the drain for a joke. This kind of items were deemed unacceptable. When the Red Cross adopted the phrase “Pull my finger” as the slogan for its campaign to enhance donations of flatulence for disaster victims, a classic joke was in essence misplaced forever.


For a long time, the major supply of flatulence for medicinal functions was that donated by humans. As human flatulence has never conformed to a predictable routine, personal waste-gasoline assortment attachments, or “belt balloons”, became a frequent web site. As use and demand boost, much flatulence was ultimately harvested from domestic cows, a practice which had the sudden but appreciated consequence of slowing global warming.


With flatulence encouraged, folks started out eating much more flatulence-creating foodstuffs, especially these foods that included beans and a lot of spice, resulting in Mexican cuisine reaching global dominance in underneath a month.


As is usually the situation with significant social adjustments, specific men and women were unable or unwilling to adapt. These who refused to embrace flatulence and donate their emissions simply because they regarded it rude or vulgar were ultimately labelled “too grand to guff”, and in a cruelly ironic twist, sooner or later became social outcasts.


There have been, of program, a lot of damaging consequences. The makes use of of flatulence in mainstream medication lead to the underlying ideas getting seized on and speedily corrupted by alternative medication adherents. The concept that “if a single bodily emission cures illnesses, they all do” rapidly took hold, and lead to an improve in spread of illnesses as sick individuals had been coughed on, sneezed on, belched on or… worse, by people who claimed that carrying out so would help them.


A lot of also criticised the reversal of the public smoking ban in the Uk, which occurred following effective campaigns based on the truth that improved flatulence had now created public areas smell far worse than cigarette smoke ever did. Individuals who complained about the dangers of passive smoking were invariably dismissed by people who pointed out that the healing properties of farts will cancel them out. Some pubs and dining establishments experimented with to introduce focused “farting areas” on their premises, but these so-referred to as “Dutch ovens” never ever actually caught on.


And as ever, it was Ryanair who delivered the most shameless attempt to money in on the therapeutic positive aspects of intestinal gasses, by cutting back on the air filtering on their flights and charging passengers an extra “indirect gaseous medicinal administration” fee.


At this stage, you might be thinking “but this is nonsense none of this occurred, it is just somebody with a media platform extrapolating wildly from anything an individual else wrote and presenting it as fact”.


Yes, that is precisely what it is. But as we saw in the initial 2 paragraphs, this sort of issue is apparently fine.


Dean Burnett prefers to supply his unpleasant outbursts by way of the odourless medium of Twitter, @garwboy



Silent, not deadly how farts remedy conditions | Dean Burnett

16 Mayıs 2014 Cuma

Diabetes and me: how silent killer caught up with NHS chief

‘I just knew one thing was wrong with me. For a number of months I had been turning out to be more and more, unusually tired and was needing to go to the toilet five or 6 instances a evening. I knew it was not overwork or tension but did not know what it could be. My wife Sarah-Jane thought I was just a bit rundown.


This was in direction of the end of 2012. Nevertheless, the travelling concerned in getting chief executive of the NHS, the birth of my daughter Rosa that November and the reality that I would just moved home meant I didn’t get round to seeing my GP till Christmas Eve, a although right after the symptoms appeared.


Pretty much correct away my GP said: “It sounds like diabetes to me”. He took some blood, put it into a machine and it showed that my blood glucose degree was way past what it should be. That confirmed that I had type two diabetes.


He said: “You’re going to the toilet a good deal as your kidneys are responding to large ranges of sugar in your blood and your body deals with that by urinating it out.” I stated, ‘Can I be cured? Can I get out of this?’ But he explained, ‘No, you have acquired it for life.”


He also explained that the principal problems of diabetes are heart failure, stroke, kidney failure, blindness and amputation of a decrease limb. I knew all that currently I would offered proof to the public accounts committee about diabetes a few months earlier, ironically. But to hear a medical professional saying this to me about me was sobering and quite scary.


It was particularly sobering simply because my father, who’d been a plasterer, died when he was 68 from emphysema and asthma. He spent his final years in a wheelchair. My grandfather, a labourer in a brass factory, also died in his 60s, of heart failure.


So I’d often assumed I would die early too that I would not make 70. My expectations had been for no longer than that. It might sound weird but I was very fatalistic about that. Unconsciously I wasn’t searching right after my well being simply because I believed which is what would happen.


My sons Liam and Paul from my 1st marriage are in their 20s. I would constantly assumed I’d see them develop up. But this diagnosis of diabetes truly produced me realise that I might not be there for my small girl, Rosa. The GP stated to me: “You have to think about the subsequent 20 years and managing your situation”.


I out of the blue considered, “Oh Lord”. I often knew having a child when you are older – I was 57 when she was born – meant there was the potential to not be close to for significantly of their daily life. But suddenly the time I may possibly have began to constrict in front of my eyes. I was not pondering: “I may well only be close to right up until Rosa’s 20,” simply because, from what the GP explained about my life style and the blood sugar levels I had, the possibilities were that it would be significantly less than twenty many years.


When Liam and Paul have been younger I was generating my way in the globe and I have regretted that I didn’t invest much more time with them. So I was seeking forward to seeing much more of Rosa and currently being concerned in her expanding up – becoming a father once more was wonderful – but all of a sudden I realised I would not have significantly time at all. The notion that I wouldn’t even see her go to secondary college manufactured me think: “What on earth am I carrying out right here? How have I received myself into this spot?” That was all fairly bleak.


My GP didn’t say it like this, but it felt like he was saying “it really is your personal fault”, due to the fact it’s a life-style-relevant ailment. It felt like he was saying: “The way you eat, your lack of exercising – individuals things are producing this diabetes for you”.


That’s fairly challenging to hear: the diagnosis, then the issues, and then “by the way it’s your fault”. But in reality, it was definitely, entirely my fault.


I had lost management of my overall health and my life style. I had essentially abdicated responsibility for my personal overall health and allowed it to get out of control, even however I was the chief executive of the NHS. The irony of that was large, I know, not least since I utilised to stand on stage regularly and speak about wellness and healthcare. In all that time only one particular particular person pointed out to me the dissonance in between what I was saying and what they noticed on stage. The way I dealt with that dissonance was to say to myself: “Yeah but I am healthful, I’m fine, I am not off sick, I’m robust.”


But I was deluding myself totally deluding myself. That’s why they contact diabetes the silent killer. You can reside with it for a lot of years and not know you have got it since you will not truly feel sick all the time, but all these alterations to your body are going on. It does not involve discomfort, or growths, or chemotherapy or something like that, but kills people, just like cancer. It’s just not evident to men and women that you’ve got it. In reality there are three instances as several diabetics as men and women with cancer.


For years my life style was fully and utterly unhealthy. My jobs in the NHS meant I was away from residence a good deal 3, four or even 5 nights a week. Each morning in the hotel I’d have bacon, egg, sausage, tomato and fries for breakfast, then there’d be a dinner most nights. I was at railway stations and motorway service stations a good deal and would buy a triple-decker sandwich, muffin and bag of crisps – immediate gratification, truly. I would always worked hard but following I separated from my very first wife in 2001 I became obsessed with function, worked 24/7 and was never off-duty. My own overall health was the final issue on my thoughts, especially when I was single, till Sarah-Jane and I moved in with each other in 2009.


I did not feel about the implications right up until I began growing out of all my clothing. Thank heaven for Marks and Spencer’s elasticated waist trousers. They enable huge self-deception and are a excellent boon to any person who’s placing on weight. I bought them with a 38 or 40-inch waist, but they expanded, so I could kid myself that my excess weight was not as gross as it was, but really it was. When I noticed the GP that Christmas Eve I weighed 111 kilogrammes – 17 stone and six lbs. Hunting back, I had been in denial. I couldn’t really see how that could have happened, because in my personal thoughts I was considerably lighter than that. So that was really a shock, how large I’d become. But it had happened over time. I would not perceived any change. And I would never, ever weighed myself. Although I’m quite reflective about things I do, I was in no way really reflective about what I looked like.


When the GP said: “You’ve received diabetes”, I appreciated right away how serious and life-altering that was. When I was the NHS chief executive folks utilized to say that I famously had “grip”, that I knew what was going on and was in charge certainly that was element of people’s criticism of me. So I realised I had to get a grip on my life style and resolved to take manage of my well being. I knew that if I actually, genuinely organised myself I could do it.


The GP needed to give me a glucose-reducing drug. When I mentioned no, I want to do it by diet regime and exercise, he was sceptical. Offered my background he didn’t actually believe I could do it that way. But that is what I made a decision, to consider to take back management without using medicines. I keep in mind my dad usually had a large bag of pills with him all the time in the final handful of many years of his life, when his emphysema took in excess of his lifestyle and meant he could not even get up the stairs, and I connected tablets with that. There was no stage resolving to go to the fitness center three occasions a week, as my extremely active daily life wouldn’t permit that. So I commenced taking a vigorous half an hour’s physical exercise every day, which the expert diabetes nurse advised as something that could support a good deal. My personnel started out reserving me into hotels that were at least half an hour’s stroll from wherever it was I had to be, so I could walk there.


The dietary side was far more challenging due to the fact my capability to delude myself on this is very great. In quick I fully overhauled my diet program. I started to realize about and use low-GI meals, such as basmati rice and wholegrain bread, and also have brown bread, brown rice and brown pasta as an alternative of their white equivalents. That made a enormous distinction to my glucose amounts. Some diabetics get a small machine and a set of strips which you use when you do a tiny blood check on your self four occasions a day, to verify your glucose amounts. You seem at your score and you fill it in a book so you can see the trajectory of it.


I was often keen on numbers and targets in my NHS work, as performance managements tools, so I used the targets for what my glucose amounts must be as a motivational instrument. When you do your blood test before a meal the number need to be under 7, but if you do it two hours after you’ve eaten it requirements to be below 10, since it goes up when you consume and then goes down yet again. So I saw the impact that consuming specific items at particular times had on my numbers.


I have reduce out nearly all sauces. I have discovered portion management is essential. For illustration, I now measure out the amount of pasta I should be consuming, which turns out to be about a quarter of the volume I utilised to eat. Previously if Sarah-Jane hadn’t completed her food I’d consume that also. I’ve stopped that. I am far more demanding in restaurants. I say: “Never put chips on the plate., as that is temptation, or “no butter, just plain as it is”.


I now eat grilled fish and do not eat as well much bread. I do not have starters and consume nothing at all in between meals except maybe a small bag of tomatoes, chopped peppers or cucumbers. One particular of the motives I determined to inform folks I had diabetes was that if you are out consuming with individuals and somebody says “have the chips”, if you say you happen to be making an attempt to get rid of excess weight they say “oh go on have them anyway”, whereas if I say “I have diabetes” they don’t. In a unusual way men and women are a lot a lot more supportive of you if they feel you’ve acquired a disease you are tackling rather than dieting.


You see the exact same point when individuals say “have an additional pint”. I was brought up from the age of 14 to think that on Friday night it truly is eight pints of bitter, and did that by means of my 40s and into my 50s. Each Friday evening I’d go out and have 7 or eight pints. But I’ve now minimize out beer altogether. Previously I would have an alcoholic drink of some kind 3 nights out of four. Now I have two tiny glasses of red wine twice a week. So I’ve undergone a dramatic revolution in my way of life. I have lost about 3 stone and am carrying out my ideal to hold my fat down.


Regardless of that I am now one of about three.2m folks in the Uk who have been diagnosed with diabetes. Some 225,000 a lot more are diagnosed every 12 months. Another 600,000 or so with variety two are nevertheless undiagnosed, so the actual total is about 3.8m. 90% of diabetics have sort 2, which is linked with way of life and obesity, whereas variety one is an autoimmune situation.


I don’t go along with the see that diabetes is going to “overwhelm” the NHS, because that suggests it truly is like a tsunami – some thing you can’t do anything at all about. But it does currently price the NHS about £10bn, about 10% of the price range. Diabetes United kingdom say it will be 17% of the price range inside of a generation.


When I visited a hospital in Birmingham a few months in the past I found 28% of the inpatients had diabetes. Expert diabetes medical professionals say which is fairly standard. It is obviously a enormous and increasing burden on the NHS.


So diabetes is a terrifying phenomenon as properly as a horrible illness. It is incurable and existence-limiting. It is also actually fairly easy to get, as I discovered. As a country we need to have a wake-up phone about diabetes. But it is also one thing we can and must do much much more to avoid and aid individuals deal with it greater when they get it. If we can tackle diabetes we will minimize the amount of heart attacks and strokes related to diabetes, which is concerned in about 24,000 early deaths a 12 months in England and Wales, and also lessen the 6,000 reduce limb amputations that happen each 12 months, about 80% of which are preventable. It’s the complications of diabetes rather than the diabetes itself that kills folks.


To prevent it and control it entire households need to have to modify the way they consume and reside. We want to advertise wholesome living and make that simpler. We require simpler access to major care to assist ensure earlier diagnosis. Significantly more money ought to go into the Specialist Patient Programme, which helps men and women manage their condition. I located that very helpful. Better use of education, engineering and social psychology would aid, as well.


But men and women also require to consider handle of their personal health, as I’ve now completed, irrespective of regardless of whether they are diabetic or not. It is achievable to change, however which is seldom straightforward. Partners are important, as well. If the husband or wife of somebody with diabetes says: “I’m going to preserve on eating chips and cake and pie and you can sit opposite me with a lettuce leaf”, that’s not going to perform. It’s very good for partners too when these sorts of adjustments take place. I’m now our household shopper. We all only eat what I acquire. My wife’s found brown bread and has misplaced excess weight also and is satisfied about that.


I am now much far more confident about seeing Rosa expand up. I feel I have done every little thing I can to make sure that our partnership goes on as lengthy as feasible. I hope that by managing my diabetes as greatest I can I am extending my life. I genuinely want to be about for as extended as I can.”



Diabetes and me: how silent killer caught up with NHS chief

9 Mart 2014 Pazar

"Silent epidemic" of brain harm and dementia triggered by concussion in rugby and other sports


O’Driscoll, who resigned from the IRB healthcare advisory board two many years in the past in protest at its managing of head injuries, cites the therapy of his own nephew, Brian O’Driscoll, as evidence of the difficulty.




Speaking at the movie premiere last week, Alex Corbisiero, the England and Lions player, said the game’s protocols for dealing with concussion have been “laughable”.


Former players Lewis Moody and Rory Lamont have the two also named for stricter controls, suggesting the choice to return to play ought to be taken by doctors since players would be too influenced by their own occupation conisiderations.


Head injuries can enhance the risks of dementia, in specific persistent traumatic encephalopathy (CTE).


Although boxers had been lengthy acknowledged to be at danger of brain damage, the risk from other make contact with sports has only far more just lately turn into recognized.


Chris Bryant MP, a former amateur player, has called for a parliamentary inquiry into the way sports activities deal with the situation of concussion, warning that lawsuits above the concern could otherwise be a “real possibility”.


Such lawsuits have previously been seen in the US, the place four,500 former American football players launched a class action suit towards the NFL, accusing the league of hiding the dangers of brain injury after analysis showed that former gamers were getting impacted by CTE.


A district judge in January rejected a proposed $ 765m settlement, suggesting it was inadequate to cover all retired players who would eventually be diagnosed with injuries.


In November the Rugby Football Union set up a operating group to study the link between numerous concussion and dementia.




"Silent epidemic" of brain harm and dementia triggered by concussion in rugby and other sports

29 Aralık 2013 Pazar

2nd-Hand Snoring: The “Silent” Killer

Couples all too often accept their partner’s snoring as an annoyance of marriage.  Nevertheless worse, sleep deprivation that the non-snoring spouse is enduring from 2nd-hand snoring is deadly.


A study conducted with the Federico II University in Naples, Italy, aggregated decade-prolonged research from about the planet involving far more than 1.3 million individuals and discovered “unequivocal proof of the direct link” among lack of rest and premature death.  A 2010 examine examined the impact of brief rest on mortality and located that individuals with “.. much less than 6 hours of sleep a evening had been four instances more very likely to die more than a 14-12 months time period. “   Lack of rest also leads to depression, stroke, memory reduction and more.


Analysis has proven snoring is quite frequently a symptom of persistent inflammation.  Irritation is caused by several diverse variables which includes allergies, well being, and diet program.  Snoring will be silenced completely by identifying the underlying situation and insisting adjust.


Identify the Culprit


Widespread allergies are a component of existence for hundreds of thousands of Americans.  Pet dander and pollen are just a few of the sneaky offenders leaving folks miserable for days or weeks at a time.  White blood cells rush to the nasal passages creating inflammation and muscle weakness.   WebMD suggests visiting your doctor and taking a skin check.  A tiny amount of allergens are placed on or under the skin and a reaction will occur on a good consequence.  Final results might be quick or up to 72 hrs dependent on the check.


When allergy symptoms are not the perpetrator the subsequent stage is to make diet changes to lessen continual inflammation.  Persistent irritation is extremely very likely the result of an unbalanced diet regime.  In excess of historical past, humans have evolved from a diet of hunter gatherer’s to domestication of livestock and farming.  A diet heavy in complicated cereals and meat is fairly new to the human diet and we have not nevertheless totally evolved to digest it.  The contemporary diet program changed substantially to include significantly increased ranges of Omega-6 (n-6) fatty acids and less Omega-three (n-3).  People evolved on a ratio of one:1, n-three/n-6, even so now with calories getting derived from plant oils, this kind of as soybeans, some individuals have a ratio as large as 25:1!


Fight Back


Make your companion sing in the shower!  Regardless of meals allergens we need to have to strengthen and tone our throat muscles.  Sing for 5 minutes every day for two weeks and you should start seeing outcomes.  If this does not perform, then the snoring spouse demands to proceed doing work on their diet program.


If your partners has allergies then a number of all-natural and pharmaceutical options are accessible.  Talk to your medical professional or nutritionist about the very best methods to cope with allergy signs.  Often medicine in conjunction with modest life style changes can have fantastic positive aspects.


Insist your partner steer clear of pro-inflammatory foods (something processed or containing flours) and increase anti-inflammatory food items (fresh produce and marine algae).   Eating basic structured food is easy for the entire body to digest and soak up.    Wheat and flour have complicated molecular structures that our digestive method has not evolved to tolerate in heavy loads.   Compared to terrestrial plants, the Globe Well being Organization states that “…algae-derived marine oils incorporate the longer-chain docosahexaenoic (DHA) and eicosapentaenoic (EPA) acids.“   EPA (an omega-3) is a precursor to different class of anti-inflammatory eicosanoids.   Adding reside marine algae to our everyday diet regime will ease the constriction of blood vessels and significantly reduce inflammation.


Sleep is one particular of the most important activities to staying healthy.  Disrupted sleep from a partner will commence an avalanche of troubles like depression, aging skin, fat obtain, and improved danger of death.  Snoring is comparable to giving off 2nd-hand smoke!  If your companion snores then take action for you personal overall health.


http://www.who.int/elena/titles/bbc/fish_oil_pregnancy/en/


http://www.ncbi.nlm.nih.gov/pubmed/24086169


http://www.ncbi.nlm.nih.gov/pubmed/19022225


www.webmd.com


http://www.naturalhealthmag.com/specialist-suggestions/how-can-i-end-snoring


http://information.discovery.com/human/rest-insomnia-well being.htm



2nd-Hand Snoring: The “Silent” Killer