9 Temmuz 2014 Çarşamba

Tackling the mystery of Alzheimer"s, and consciousness itself | @guardianletters

Scan to detect Alzheimer

A scan to detect Alzeimer’s condition. Photograph: Alamy




The development of novel biomarkers to identify sufferers at higher danger of developing Alzheimer’s dementia is encouraging and will hopefully translate into exams that can be used clinically (Blood test breakthrough in search for Alzheimer’s remedy, 8 July). Nevertheless, the diagnosis and treatment of dementia is multifaceted and there are a number of locations that require urgent consideration now. Although there is no cure for dementia, recent therapies can slow the progression of the illness, even if only for six months. Clearly more study is needed to develop better therapies, but recent therapies are related with modest enhancements in cognition and perform that are invaluable to patients and their families. It is essential that as analysis progresses so also do our clinical providers, incorporating equitable access to drug therapies and professional input.


The care that patients with dementia require cuts across classic speciality boundaries. Efficient care calls for collaborative functioning between a number of disciplines like basic practice, geriatric medicine, psychiatry and social services. On the ground, a amount of alterations want to get place such as raising awareness of the issue among non-specialists, incorporating basic healthcare experience into psychiatric instruction and making certain patients’ information can be transferred between various care settings. Some of these modifications can be implemented comparatively rapidly and other folks will get longer. Even so, to be implemented effectively, capabilities and attitudes will want to change amongst care professionals and there will want to be political/monetary support. In these occasions of austerity it is crucial that the practicalities of caring for men and women with dementia are not misplaced. 
Dr KD Jethwa
Former academic clinical fellow in psychiatry, University of Warwick 


• The publication of study that could allow a check to predict the onset of Alzheimer’s far earlier than presently achievable is really welcome, particularly as the burden of the disease will rise across the globe in the potential. Nonetheless, there is even now a lot to be accomplished to increase the diagnosis of Alzheimer’s, specifically in the Uk, as entry to early and accurate diagnosis and treatment can vary significantly. A current worldwide survey, commissioned by GE Healthcare between physicians and sufferers, discovered that 50% of Alzheimer’s patients in the United kingdom have to wait for up to 3 months for an MRI scan, an vital component in the diagnosis of dementia. This compares with ten% in the US and 15% in Germany. For PET scans, more and more critical for diagnosing neurological issues, 44% of Uk sufferers wait a lot more than three months, compared with 6.5% in Germany and twelve% in France.


The survey located that up to twenty% of individuals with progressive neurological ailments, like dementia, face the probability of getting incorrect treatment method whilst waiting for their diagnosis. Meanwhile, their issue can carry on to deteriorate, and the patient is exposed to the pointless anxiousness and tension of not realizing. Two-thirds of people surveyed said it was worse not to know what problem they had than to acquire a confirmatory diagnosis.


Accessibility to early and correct diagnostic tools is vital with neurological illnesses, affording the prospective of both better clinical outcomes and an improved quality of life. With the prevalence of dementia on the increase, more powerful diagnosis and management is essential. We hope that the likely of this analysis can be constructed upon to create an effective check for Alzheimer’s.
Karl Blight
General manager, GE Healthcare Northern Europe


• Current advances in brain imaging have taught us a good deal about how the brain, rather than the thoughts, performs (Arguments more than brain simulation come to a head, 7 July). Philosophers have failed above the centuries to explain the connection in between brain and mind, and scientists have prevented obtaining concerned in such conjectures, resulting in the “new age phrenology” we now see. An IT undertaking purporting to simulate the exercise of an entire human brain is not only premature, on account of its naive assumptions about complexity, but, except if the simulation benefits in an emergent house such as self-determination, it is doomed to failure. And since no one particular can think about how this kind of a house could be programmed to emerge, any this kind of emergence would remain as much a mystery as that of consciousness itself: the very difficulty that the task is created to help remedy.
Dr Allan Dodds
Clinical neuropsychologist, Nottingham




Tackling the mystery of Alzheimer"s, and consciousness itself | @guardianletters

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