11 Haziran 2014 Çarşamba

Retina grown from stem cells could permit blind to see once again

The retina is the layer of photo-sensitive cells and neurons at the back of the eye that converts light signals into nerve messages transmitted to the brain.


In the course of the experiment, Dr Canto-Soler’s crew had been capable to motivate initial growth of the retina, which then continued building on its own.


“When we started this work, we didn’t think stem cells would be ready to create up a retina virtually on their own,” Dr Canto-Soler said. “In our technique, somehow the cells knew what to do.”


At a stage equivalent to 28 weeks of foetal growth, the scientists tested the mini-retina by exposing it to pulses of light. They found that the lab-grown photoreceptors responded to light the same way as they do in the human eye.


Dr Canto-Soler, whose analysis is published in Nature Communications, said the method opened up the likelihood of generating hundreds of mini-retinas at a time from a man or woman impacted by blinding diseases.


These could be utilised to examine the triggers of retinal ailments in human tissue, rather than relying on animal versions.


Medicines tailored to personal patients could also be examined on the structures. In the prolonged term, diseased or dead retinal tissue could be replaced by laboratory-grown cells to restore vision, Dr Canto-Soler extra.


Age-relevant macular degeneration, which is induced by a dilemma with the retina, is the major cause of visual impairment in the United kingdom, affecting up to 500,000 men and women, according to NHS figures.


It is most frequent in folks more than 50, with one in ten people in excess of the age of 65 thought to be struggling from the issue to some extent.



Retina grown from stem cells could permit blind to see once again

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