When Hollie was recovering from her very first round of blood transfusions in hospital the only way a lot of her family members could talk with her was employing FaceTime.
Her uncle Matthew Clark put his underwear on his head to make her laugh even though he was talking to her on FaceTime and it sparked an notion for the campaign which is gathering tempo on Twitter.
Welsh rugby player Sam Warburton kickstarted the viral trend when he tweeted a image of himself with pants on his and his puppy Ledley’s head.
Athlete Jamie Baulch and sports commentator Jonathan Davies have also lent help, tweeting pictures and urging people to sign up to the Anthony Nolan donor register.
Mrs Clark said: “We’ve been completely thrilled by how a lot assistance we have previously had for this campaign.
“We’ve had responses from all over the planet currently.
“Obviously we’re desperate to find a donor for Hollie but this is not just for her, we realise the influence this can have for other households in the same situation.
“Even a single additional donor signing up could transform someone’s daily life.”
Hollie, of Roath Park, Cardiff, at first had to have two blood transfusions a week to improve her issue but she has now stabilised.
Mrs Clark, a GP, mentioned: “The only achievable treatment method is a bone marrow transplant, we can’t do something else other than preserve Hollie stable with blood transfusions until we locate a donor.
“They are currently seeking the registers but we considered we cannot just sit waiting and not do anything.”
Her parents’ concern was first raised when Hollie started out building mystery bruising.
Her mother took her to their physician who ran exams and sent Hollie to hospital that night.
“It was an absolute shock, it is virtually the worst point as a mother or father you could be told,” Mrs Clark mentioned.
“We are keen to uncover a donor while Hollie remains fairly stable, we do not want it to get to a stage where she is very unwell once again which will make the method more difficult.”
Stars pose with pants on their head to assist bone marrow patient Hollie Clark
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